{"id":74701,"date":"2026-06-24T13:51:37","date_gmt":"2026-06-24T11:51:37","guid":{"rendered":"https:\/\/www.beautydecoded.com\/?p=74701"},"modified":"2026-06-24T13:51:40","modified_gmt":"2026-06-24T11:51:40","slug":"hyaluronidase-why-hundreds-of-women-accuse-this-product-of-ruining-their-faces","status":"publish","type":"post","link":"https:\/\/www.beautydecoded.com\/en\/hyaluronidase-why-hundreds-of-women-accuse-this-product-of-ruining-their-faces\/","title":{"rendered":"Hyaluronidase: Why Hundreds of Women Accuse This Product of Ruining Their Faces"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><em>Marketed as a way to completely reverse the effects of hyaluronic acid, hyaluronidase is now the subject of a wave of concerning testimonials. An investigation into a product that is essential\u2026 but far from harmless.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u00abMy skin is sagging. My face looks like a rag.\u00bb<\/strong>\u00a0This statement, made by a Russian patient in an Australian news report, has become a rallying cry. On Instagram, TikTok, and in private Facebook groups with thousands of members, women describe how their faces have been transformed\u2014sunken, sagging, \u00abaged twenty years in just a few weeks\u00bb\u2014after having their hyaluronic acid injections dissolved.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The product in question has a strange name:&nbsp;<strong>hyaluronidase<\/strong>, sold under brand names such as marques Hyalase or Hylenex. It is the injectable enzyme that has been used for over a decade to dissolve fillers that have gone wrong, migrated, or simply gone out of style. Paradoxically, it is also the main selling point for hyaluronic acid fillers:&nbsp;<em>\u00abIf you don't like it, we'll dissolve it.\u00bb<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Except that this promise deserves to be qualified.<\/p>\n\n\n\n<blockquote class=\"instagram-media\" data-instgrm-captioned data-instgrm-permalink=\"https:\/\/www.instagram.com\/reel\/DZ2ppVGMEta\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\" style=\" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);\"><div style=\"padding:16px;\"> <a href=\"https:\/\/www.instagram.com\/reel\/DZ2ppVGMEta\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;\" target=\"_blank\" rel=\"noopener\"> <div style=\" display: flex; flex-direction: row; align-items: center;\"> <div style=\"background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div><\/div><\/div><div style=\"padding: 19% 0;\"><\/div> <div style=\"display:block; height:50px; margin:0 auto 12px; width:50px;\"><svg width=\"50px\" height=\"50px\" viewbox=\"0 0 60 60\" version=\"1.1\" xmlns=\"https:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"https:\/\/www.w3.org\/1999\/xlink\"><g stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\"><g transform=\"translate(-511.000000, -20.000000)\" fill=\"#000000\"><g><path d=\"M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631\"><\/path><\/g><\/g><\/g><\/svg><\/div><div style=\"padding-top: 8px;\"> <div style=\" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;\">See this post on Instagram<\/div><\/div><div style=\"padding: 12.5% 0;\"><\/div> <div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\"><div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div> <div style=\"background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div><\/div><div style=\"margin-left: 8px;\"> <div style=\" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div> <div style=\" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)\"><\/div><\/div><div style=\"margin-left: auto;\"> <div style=\" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div> <div style=\" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div> <div style=\" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div><\/div><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div><\/div><\/a><p style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;\"><a href=\"https:\/\/www.instagram.com\/reel\/DZ2ppVGMEta\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;\" target=\"_blank\" rel=\"noopener\">A post shared by Dr. Sylvain David (@drsylvaindavid)<\/a><\/p><\/div><\/blockquote>\n<script async src=\"\/\/www.instagram.com\/embed.js\"><\/script>\n\n\n\n<h3 class=\"wp-block-heading\">An essential enzyme\u2026 that can\u2019t be demonized<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Let\u2019s be clear from the outset: hyaluronidase is a legitimate medical tool\u2014and even a lifesaver in certain situations. In particular, it is the antidote used in emergencies when a filler compresses a blood vessel\u2014a rare but serious complication that can lead to skin necrosis or, in the most severe cases, blindness. Without hyaluronidase, hyaluronic acid fillers would lose one of their main safety advantages.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The problem isn't the molecule itself. It stems from its widespread, trivialized, and largely unstandardized use in cosmetic applications.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">An enzyme that doesn't sort<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"> Hyaluronidase has no ability to discriminate. It cleaves the bonds in hyaluronic acid, from <em>everything<\/em>\u00a0Hyaluronic acid. The kind that was injected into your lips six months ago, and the kind your skin has been producing naturally since birth.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The Real Problem: Concentration<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">This is where the difference between a successful dissolution and a transformed face lies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Hyaluronidase is sold in powder form. Some practitioners inject it at very high concentrations, \u00abto be sure\u00bb that the filler will be completely removed. This approach, while well-intentioned, is reckless and exposes the surrounding tissues to a massive dose of the enzyme.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A school that is gaining increasing recognition, on the contrary, advocates a\u00a0<strong>significant dilution<\/strong>. This solution is more than sufficient to dissolve the filler, while significantly reducing the impact on natural tissues. <\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What Patients Report<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The testimonials share some striking similarities: a feeling that the skin \u00abisn\u2019t holding up anymore,\u00bb a gaunt face, and a loss of definition in the cheekbones.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The other possibility that no one mentions<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">However, not everything can be attributed to hyaluronidase. A significant portion of the \u00abaesthetic shock\u00bb following dissolution stems from a real psychological phenomenon:&nbsp;<strong>acclimatization<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When a person has been receiving injections for eight, ten, or twelve years, their face has continued to age\u00a0<em>under<\/em>\u00a0The filler. He simply didn\u2019t notice it. The day the enzyme breaks down that artificial volume, she suddenly discovers the cumulative effect of a decade of natural aging. The contrast is stark\u2014not because the product destroyed her, but because she had never seen her true face.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Added to that is the\u2019<strong>balloon effect<\/strong>&nbsp;: Tissue that has been chronically stretched by fillers never fully returns to its original shape. It\u2019s like a deflated balloon that retains a certain amount of worn-out elasticity. This phenomenon has nothing to do with the enzyme; it is a direct result of years of injections.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The two mechanisms\u2014the breakdown of natural tissues due to overdose and the sudden manifestation of previously hidden signs of aging\u2014coexist. This is what makes the issue so difficult to resolve.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The moral of this story<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Hyaluronidase isn't the devil. It's a remarkable tool, indispensable in vascular emergencies, and generally safe when administered in the proper dilution and by an expert. The danger isn't the molecule\u2014it's the\u00a0<strong>protocol<\/strong>\u00a0into which it is injected, and the\u00a0<strong>hand<\/strong>\u00a0who is holding the syringe.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The real takeaway is something else entirely. Hyaluronic acid fillers have been marketed for years as a completely reversible procedure. That promise deserves an asterisk. Yes, they can be dissolved. But you can\u2019t turn back time. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Both injections and dissolutions are medical procedures. They require the same standards: an experienced practitioner, a thorough understanding of anatomy, and the humility to recognize that no procedure performed on the face is ever fully reversible.<\/p>","protected":false},"excerpt":{"rendered":"<p>Marketed as a way to completely reverse the effects of hyaluronic acid, hyaluronidase is now the subject of a wave of troubling testimonials. An investigation into a product that\u2019s indispensable\u2026 but far from harmless. \u00abMy skin is sagging. My face is like a rag.\u00bb This statement, made by a Russian patient in an Australian news report, has become a cry of\u2026<\/p>","protected":false},"author":120,"featured_media":24065,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-74701","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites"],"acf":[],"taxonomy_info":{"category":[{"value":1,"label":"Actualites"}]},"featured_image_src_large":["https:\/\/www.beautydecoded.com\/wp-content\/uploads\/2025\/02\/skincare-and-beauty-concept-1024x683.jpg",1024,683,true],"author_info":{"display_name":"Sylvain David","author_link":"https:\/\/www.beautydecoded.com\/en\/author\/beautydecoded\/"},"comment_info":2,"category_info":[{"term_id":1,"name":"Actualites","slug":"actualites","term_group":0,"term_taxonomy_id":1,"taxonomy":"category","description":"","parent":0,"count":307,"filter":"raw","cat_ID":1,"category_count":307,"category_description":"","cat_name":"Actualites","category_nicename":"actualites","category_parent":0}],"tag_info":false,"_links":{"self":[{"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/posts\/74701","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/users\/120"}],"replies":[{"embeddable":true,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/comments?post=74701"}],"version-history":[{"count":3,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/posts\/74701\/revisions"}],"predecessor-version":[{"id":74706,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/posts\/74701\/revisions\/74706"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/media\/24065"}],"wp:attachment":[{"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/media?parent=74701"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/categories?post=74701"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.beautydecoded.com\/en\/wp-json\/wp\/v2\/tags?post=74701"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}