APLB («A Plus B») is a South Korean K-beauty brand with a «gentle yet effective» positioning - concentrated active ingredients and maximum tolerance. Analyzed catalog of 111 references through the BeautyDecoded database. average sensitive skin score +1.56 (median +2.00): the most favorable tolerance profile ever observed on the panel. Hyaluronic Acid Ceramide HA B5 Ampoule Serum reaches +3.55 - a new absolute BD record. Four patented technologies structure the catalog (Liposome, Spicule, Exosome, LIPO GLUTA NIAC CEN). Global bestseller Glutathione Niacinamide in communicated concentrations: Niacinamide 20,000 ppm + Glutathione 1,000 ppm + Centella 29.2 %.
The BeautyDecoded application lets you scan any cosmetic product to visualize its suitability for your skin type and needs, based on INCI analysis - particularly useful for arbitrating among the 35+ thematic lines in the APLB catalog according to your main objective (anti-spot, anti-aging, barrier restoration, anti-imperfections) and your skin tolerance level.
APLB is a South Korean K-beauty brand positioned in the contemporary active-centric segment with an explicit philosophy: «gentle yet effective» - formulations with high concentrations of documented active ingredients, Skin Irritation Tested and EWG Green Grade, designed to be tolerated by sensitive skin despite their high active content. BeautyDecoded's analysis of 111 references objectively confirms this formulatory claim : average sensitive skin score +1.56 (median +2.00) the most favorable algorithmic tolerance profile ever observed on the panel as a whole (higher than TIRTIR +0.12 which held the previous record, Theramid -0.68, Acnemy -1.85, On The Wild Side -2.71). And all this despite a catalog containing serious concentrated actives in claimed concentrations Niacinamide 20,000 ppm (2 %), Glutathione 1,000 ppm (0.1 %), Centella 29.2 %, encapsulated retinol, azelaic acid, tranexamic acid, salicylic acid, mandelic and lactic AHAs. The catalog is organized around more than 35 distinct thematic lines, each focusing on a specific combination of active ingredients (toner, mist, serum, cream, sometimes suncare). The two main categories are complexion-enhancing (Glutathione Niacinamide, Tranexamic Acid Niacinamide, Zinc Niacinamide, Kojic Acid Vitamin C, Ferulic Acid Vitamin C) and anti-aging (Retinol Vitamin C Vitamin E, Collagen EGF Peptide, Coenzyme Q10 Retinol, PDRN Vitamin C, Mandelic Acid Retinol, Lactic Acid Retinol, Snail Mucin Ginseng). Four patented technologies structure our formulations : LIPO GLUTA NIAC CEN™ (signature liposomal encapsulation at 31.3 % of Glutathione Niacinamide), Liposome (phospholipid encapsulation), Spicule (cosmetic microneedling via sea sponge spicules - Shot 180 retinol, Shot 260 niacinamide, Shot 300 collagen), Exosome (regenerative cell vesicles).
Visit Hyaluronic Acid Ceramide HA B5 Ampoule Serum scores +3.55 for sensitive skin - the highest score ever observed among all references analyzed by BeautyDecoded, marques included (previous record: Cica Care Serum TIRTIR at +3.25). The formulation is built around four documented pillars : (1) multi-molecular-weight hyaluronic acid (simultaneous surface hydration + epidermal depth); (2) multiple ceramides documented as the main constituents of the stratum corneum's intercellular cement; (3) panthenol B5 - soothing, barrier-restoring provitamin (Ebner F, Am J Clin Dermatol, 2002); (4) centella asiatica with its isolated active compounds (Madecassoside + Asiaticoside + Asiatic Acid). Redness score 76.5 consistent with soothing profile. Modest anti-aging score 68.0: it's not a corrective anti-aging product, it's a routine serum to preserve and restore the skin barrier. The complete HA B5 Ceramide range comprises 4 products with outstanding tolerance scores. Ampoule Serum (+3.55 record), Cream (+3.30), Mist Essence (+3.30), Facial Toner (+3.30) - building a 100 % restorative barrier routine exclusively HA B5 Ceramide for the most critical periods (post dermatological CO2 fractional laser procedure or deep peel, rosacea flare-up, stabilized adult atopic dermatitis).
The most impressive feature of the APLB catalog is its serums with active ingredients that are usually irritating. Where these assets typically generate unfavorable sensitive skin scores (-3 to -6), APLB achieves unusual results. Azelaic Acid Peptide Ampoule Serum Sensitive skin score +3,00 with redness 78.2 - this is probably the best-tolerated azelaic acid formulation on the world market (vs AZID Theramid at +0.1, TIRTIR Azelaic 12 % at +0.25). Tranexamic Acid Niacinamide Ampoule Serum Sensitive skin score +3,00 - this is remarkable for a serum containing tranexamic acid (an anti-melasma active documented in dermatology, Lee HC, Dermatol Surg, 2016). Salicylic Acid BHA Arbutin Ampoule Serum Sensitive skin score +3,00 - BHA + arbutin + niacinamide usually irritating in combination, here neutralized by the centella + B5 cocktail. Liposome Retinol LX Serum Sensitive skin score +1,05 with anti-aging 88.4 - this is probably the best-tolerated cosmetic retinol on the consumer market, thanks to liposomal encapsulation. The formulative explanation is coherent Each powerful active ingredient is combined with a systematic support cocktail (centella 29.2 % + niacinamide + panthenol B5 + hyaluronic acid + soothing extracts - lotus, mugwort, rice, saccharomyces ferment, tea tree, signature eggplant). This soothing multi-active layering is the contemporary K-beauty signature of quality, here pushed to the limit.
" APLB is probably the most versatile and best-tolerated brand on the BeautyDecoded panel to date.. The average score for sensitive skin of +1.56 (median +2.00) - an absolute record - combined with the richness of the catalog (111 references covering 35+ thematic lines) makes it a relevant brand for virtually all skin profiles, with a special mention for sensitive skin profiles seeking to introduce concentrated active ingredients (retinoids, vitamin C, azelaic acid, tranexamic acid) without the usual risk of irritation. Three formative nuggets deserve a special mention : (1) HA B5 Ceramide Ampoule Serum (+3.55 - BD absolute record), now the panel's leading reference for barrier restoration in post-dermatological procedures, rosacea flare-ups and stabilized atopic dermatitis; (2) Liposome Retinol LX Serum (anti-aging 88.4 + sensitive +1.05), which redefines what can be expected of a mainstream cosmetic retinol in terms of efficacy/tolerance ratio - a particularly relevant option for first-time users and sensitive skin that has failed on conventional retinol; (3) Glutathione Niacinamide Ampoule Serum (K-beauty's worldwide bestseller) with communicated concentrations (Niacinamide 20,000 ppm + Glutathione 1,000 ppm + Centella 29.2 %) at a very affordable price (€10-15) - a tolerant, multi-mechanism anti-spot reference. Honest nuance to point out The two unfavorable references identified in the full analysis - Glutathione Niacinamide Body Wash (-5.25, consistent with the detergent nature of a shower gel, to be used with a quick rinse without prolonged application), and Retinol Vitamin C Vitamin E Sunscreen (-2.20, consistent with a retinol-containing sunscreen - a combination usually not recommended as it is photo-sensitizing). For use on sensitive skin, Glutathione Niacinamide Sunscreen (-1.25) is preferable. Editorial recommendations (1) for most reactive skin, post-procedure, stabilized atopic skin, rosacea skin, build the 100 % HA B5 Ceramide routine (toner + mist + serum + cream); (2) for the corrective anti-aging, Liposome Retinol LX is the reference to be integrated into a progressive cure; (3) for hyperpigmentation and melasma, combine Glutathione Niacinamide (morning) + Tranexamic Acid Niacinamide (evening) with mandatory SPF50+ mineral; (4) strictly contraindicated during pregnancy and breast-feeding All lines containing retinol (Liposome Retinol, Coenzyme Q10 Retinol, Mandelic Acid Retinol, Lactic Acid Retinol, Retinol Vit C Vit E, Spicule Retinol Shot 180).»
APLB relies on four distinct galenic platforms, each with a documented function. Mapping of technologies with their formulatory role and respective level of proof.
| Technology | Mechanism | Catalog presence |
|---|---|---|
| Liposome | Phospholipid encapsulation - sustained release + oxidation protection + better skin penetration (Pierre MB, Arch Dermatol Res, 2011) | Liposome Retinol LX, Liposome Vitamin C LX, Liposome Niacinamide LX |
| Spicule (Shot 180/260/300) | Spongilla marine spicules - biodegradable micro-needles that create micro-channels in the skin to optimize penetration of active ingredients (cosmetic microneedling) | Shot 180 (retinol), Shot 260 (niacinamide), Shot 300 (collagen) |
| Exosome | Extracellular vesicles 30-150 nm - emerging platform for targeted transport of actives (Yang G, Mater Today Bio, 2024) | Exosome Collagen EX, Exosome Niacinamide EX, Exosome Vitamin C EX |
| LIPO GLUTA NIAC CEN™ | Signature Complex 31.3 % - Liposomal Glutathione + Niacinamide + Centella 3X Complex | Complete Glutathione Niacinamide range (worldwide bestseller) |
APLB objectively stands out from the panel in terms of its sensitive skin score. Comparison with contemporary active-centric K-beauty references (TIRTIR), clinical premium (Theramid), specialized anti-acne (Acnemy).
| Criteria | APLB | SHOOT | Theramid | Acnemy |
|---|---|---|---|---|
| Origin | South Korea | Korea 2016 | Spain (NicheBeautyLab) | Spain 2020 |
| Refs analyzed | 111 / 35+ lines | 27 / 8 ranges | 10 serums | 19 references |
| Sensitive medium | +1,56 RECORD | +0,12 | -0,68 | -1,85 |
| Sensitive median | +2,00 RECORD | +0,50 | -0,35 | -0,70 |
| Anti-aging max | 88.4 (Liposome Retinol) | 90.1 (Vit C24) | 95.2 (Clinical Vit A) | 66.3 (Adapazit) |
| Sensitive product record | +3,55 ABSOLUTE | +3.25 (Cica Care) | +2.5 (AZID) | +0.5 (Adapazit) |
| Technologies | Liposome + Spicule + Exosome + LIPO GLUTA NIAC CEN | K-beauty signature | Peptide stratification | Nichosome® liposomal |
| Average serum price | 10-15 € (accessible) | 25-35 € | 38-50 € | ~19 € |
A complete analysis of the catalog requires us to point out the rare references with an unfavorable tolerance profile, mainly for consistent galenic reasons. These nuances do not alter the overall assessment of an exceptionally well-tolerated catalog.
| Product | Sensitive score | Formulatory explanation |
|---|---|---|
| Glutathione Niacinamide Body Wash | -5,25 | Consistent with the detergent nature of a shower gel (surfactants needed for the cleansing function) |
| Retinol Vitamin C Vitamin E Sunscreen | -2,20 | Consistent with a retinol-containing sunscreen (combination not usually recommended - retinol photosensitizes) |
Sorted by decreasingly sensitive skin score. 11 references with sensitive skin score ≥ +3.00 - a unique case on the BeautyDecoded panel. HA B5 Ceramide Ampoule Serum reaches +3.55 - RECORD ABSOLU BD. Only 2 negative-score references on 111 catalog items, for galenic reasons (shower gel, retinol suncare).
| Product | range | Sensitive score | Key score |
|---|---|---|---|
| HA B5 Ceramide Ampoule Serum | HA B5 Ceramide | +3,55 | RECORD ABSOLU BD - Barrier restoration |
| HA B5 Ceramide Cream/Mist/Toner | HA B5 Ceramide | +3,30 | Complete tolerance range - 3 formats |
| Glutathione Niacinamide Ampoule | Glutathione Niac. | +3,25 | Global bestseller - Stains 72.25 - Centella 29.2 % |
| Liposome Vitamin C LX Serum | Liposome | +3,25 | Anti-ageing 68.0 - encapsulated vit C |
| Exosome Collagen EX Serum | Exosome | +3,25 | Anti-ageing 81.6 - cell regeneration |
| PDRN Vitamin C Ampoule Serum | PDRN | +3,25 | Anti-ageing 66.3 - PDRN rare |
| Tranexamic Acid Niacinamide Serum | Tranexamic | +3,00 | Redness 91.8 - anti-melasma |
| Azelaic Acid Peptide Serum | Azelaic Peptide | +3,00 | Spots 76.5 - redness 78.2 - rosacea |
| Salicylic Acid BHA Arbutin Serum | Sal. BHA Arbutin | +3,00 | Anti-imperfections + anti-spot |
| Collagen EGF Peptide Mist | Collagen EGF | +3,00 | Anti-ageing 85.0 (TOP) - EGF + peptides |
| Snail Mucin Ginseng Serum | Snail Mucin | +3,00 | Traditional K-beauty repair |
| Glutathione Niacinamide Eye Cream | Glutathione Niac. | +2,00 | 3.79/5 out of 7 comics reviews - best-selling eyes |
| Spicule Niacinamide Shot 260 | Spicule | +1,25 | Anti-aging 79.05 - microneedling cosmetics |
| Liposome Retinol LX Serum | Liposome Retinol | +1,05 | Anti-ageing 88.4 (TOP) - tolerated retinol |
| Mandelic Acid Retinol Serum | Mandelic Retinol | +0,30 | Anti-ageing 86.7 - mandelic AHA + retinol |
| Coenzyme Q10 Retinol Serum | CoQ10 Retinol | +0,05 | Anti-ageing 88.4 - mitochondrial antioxidant |
| Glutathione Niacinamide Sunscreen | Solar | -1,25 | SPF with integrated anti-spot agents |
| Retinol Vit C Vit E Sunscreen | Retinol suncare | -2,20 | SPF + retinol - noteworthy combination |
| Glutathione Niacinamide Body Wash | Shower gel | -5,25 | Body detergent format - surfactants |
Visit new all-time record BeautyDecoded Sensitive skin score +3,55 - the highest ever observed among all panel references (previous Cica Care TIRTIR record: +3.25). The HA B5 Ceramide range comprises 4 references with outstanding tolerance scores, enabling a 100 % barrier-restoring routine.
Barrier Restoration Serum built around four documented pillars : (1) multi-molecular-weight hyaluronic acid (simultaneous surface hydration + epidermal depth); (2) multiple ceramides documented as the main constituents of the stratum corneum's intercellular cement; (3) panthenol B5 - soothing, barrier-restoring provitamin; (4) centella asiatica with its isolated active compounds (Madecassoside + Asiaticoside + Asiatic Acid). This quadruple strategy covers all documented skin barrier restoration mechanisms.
APLB's worldwide signature range, now an international K-beauty bestseller. Glutathione Niacinamide Ampoule Serum at communicated concentrations (Niacinamide 20,000 ppm + Glutathione 1,000 ppm + Centella 29.2 %), sensitive skin +3.25. Glutathione Niacinamide Eye Cream the only catalog reference with a significant user review base - rated 3.79/5 out of 7 BD reviews.
Anti-spot radiance serum based on the patented combination LIPO GLUTA NIAC CEN™ 31,3 % : Glutathione 1,000 ppm (liposomal encapsulation to optimize skin penetration), Niacinamide 20,000 ppm (2 %) (concentration within the documented effective range), Centella asiatica extract 29.2 % (the highest concentration observed on the panel). Consistent combined mechanism of action: glutathione inhibits melanogenesis at the enzymatic level (tyrosinase) and promotes eumelanin → pheomelanin conversion (Sonthalia 2018), while niacinamide blocks the transfer of melanosomes from melanocytes to keratinocytes (Hakozaki, Br J Dermatol, 2002).
Eye contour cream featuring the signature Glutathione + Niacinamide + Centella combination adapted to the periocular area. Anti-ageing score 68.0 + spots 59.5 + redness 76.5 - consistent multi-action profile for the area's major indications (dark circles, fine wrinkles, morning puffiness). Sensitive skin score +2.00 - rare for an eye contour care product with documented active ingredients.
Two advanced clinical references from the catalog. Liposome Retinol LX Serum probably the best-tolerated cosmetic retinol observable (anti-ageing 88.4 + sensitive +1.05). Tranexamic Acid Niacinamide Ampoule Serum Anti-melasma cosmetic reference with a redness score of 91.8 - one of the best on the panel.
Retinol serum built around Liposome technology - phospholipid encapsulation of retinol, enabling: (1) prolonged release of the active ingredient (reduced irritation), (2) protection of retinol against oxidation (stability), (3) improved skin penetration. Retinol is documented as the most clinically established cosmetic anti-aging active (Kafi R et al., Arch Dermatol, 2007), with activity on RAR/RXR nuclear receptors inducing collagen synthesis and accelerating cell renewal.
Serum centered on tranexamic acid - synthetic lysine analog documented in dermatology as a treatment for melasma (prescribed oral route or cosmetic topical). Mechanism of action : inhibition of keratinocyte-melanocyte interaction via plasminogen blockade, reduced tyrosinase production, and vascular anti-inflammatory action (Lee HC et al., Dermatol Surg, 2016). Tranexamic acid is one of the most effective anti-melasma agents clinically documented in dermatology..
Two advanced-technology anti-aging references. Exosome Collagen EX Serum (anti-ageing 81.6 + sensitive +3.25 - emerging exosome technology). Collagen EGF Peptide Mist Essence (anti-ageing 85.0 - one of the highest in the catalog - EGF growth factor + peptides).
Anti-aging serum based on Exosome technology - 30-150 nm extracellular vesicles released by cells, containing proteins, messenger RNA, short RNA and bioactive lipids. Exosomes are an emerging platform in cosmetology and regenerative medicine for the targeted transport of active ingredients. (Yang G et al., Mater Today Bio, 2024). In cosmetics, the exosomes used are generally of plant origin (plant stem cells) or from animal cell cultures - transparency on origin remains a point to watch in this segment. Combination with hydrolyzed collagen (bioactive peptides documented to stimulate endogenous skin collagen - Proksch E, Skin Pharmacol Physiol, 2014).
Mist anti-aging essence focused on three synergistic active ingredients : (1) EGF (Epidermal Growth Factor, sh-Oligopeptide-1) - recombinant growth factor for skin regeneration and fibroblast stimulation (Mehta RC, Plast Reconstr Surg, 2008); (2) hydrolyzed collagen - bioactive peptides; (3) additional bioactive peptides (according to complete line, usually Palmitoyl Pentapeptide-4 / Matrixyl or similar). Innovative mist format for multiple applications throughout the day (rehydration between treatments, make-up fixing with integrated anti-ageing active ingredients) - rarely seen in the European dermo-cosmetic anti-ageing segment.
Table of user profiles with recommendations based on the 111 references analyzed in BeautyDecoded.
| User profile | Interest APLB | Recommended product / alternative |
|---|---|---|
| Most reactive skin / rosacea / post-procedure | Very strong - RECORD ABSOLUTE BD | Routine 100 % HA B5 Ceramide (toner + mist + serum + cream) |
| Retinol corrective anti-aging (sensitive skin) | Very strong - best tolerated retinol observable | Liposome Retinol LX Serum (anti-aging 88.4 + sensitive +1.05) |
| Anti-spot / hyperpigmentation / melasma | Fort - justified worldwide bestseller | Glutathione Niacinamide Ampoule + Tranexamic Acid Niacinamide |
| Rosacea + blemishes / post-acne | Fort - the world's best-tolerated azelaic formulation | Azelaic Acid Peptide Serum (sensitive +3.00, spots 76.5) |
| Dark circles (phototypes IV-VI) | Strong - significant user feedback base | Glutathione Niacinamide Eye Cream (3.79/5 out of 7 BD reviews) |
| Retinoid-free corrective anti-aging | Strong - EGF + exosome performance | Collagen EGF Peptide Mist + Exosome Collagen EX |
| Preventive anti-aging (ages 25-35) | Fort - complete routine available | Glutathione Niacinamide complete + gradual introduction Liposome Retinol |
| Acne / blemishes oily skin | Strong - BHA + arbutin + azelaic tolerated | Salicylic Acid BHA Arbutin + Zinc Niacinamide + Azelaic Peptide |
| Photoprotection for sensitive skin | Moderate - prefer SPF Glutathione Niacinamide | Glutathione Niacinamide Sunscreen - avoid Retinol Vit C Vit E Sunscreen |
| Pregnant / breast-feeding women | Strong non-retinoid - avoid all retinol lines | HA B5 Ceramide + Glutathione Niacinamide + Snail Mucin Ginseng + Collagen EGF Peptide |
| Shower / body gel | Limited - detergent format with unfavorable profile | Glutathione Niacinamide Body Wash: fast rinsing without prolonged application |
«APLB is probably the most versatile and best-tolerated brand on the BeautyDecoded panel to date. The average score for sensitive skin +1.56 (median +2.00) - an absolute record - combined with the richness of the catalog (111 references covering 35+ thematic lines) makes it a relevant brand for almost all skin profiles. Three formulative nuggets deserve a special mention: HA B5 Ceramide Ampoule Serum (+3.55 - BD absolute record), now the panel's leading reference for barrier restoration in post-dermatological procedures, rosacea flare-ups and stabilized atopic dermatitis; Liposome Retinol LX Serum (anti-aging 88.4 + sensitive +1.05), which redefines the efficacy/tolerance ratio you'd expect from a mainstream cosmetic retinol; Glutathione Niacinamide Ampoule Serum (K-beauty's worldwide bestseller), with concentrations communicated at a very affordable price. Two unfavorable references were identified in the full analysis - Glutathione Niacinamide Body Wash (-5.25, consistent with the detergent nature of a shower gel) and Retinol Vit C Vit E Sunscreen (-2.20, a retinol + sun combination not usually recommended). For the most reactive skins, build up the 100 % HA B5 Ceramide routine; for corrective anti-aging, Liposome Retinol LX is the benchmark to be integrated into a gradual cure; for hyperpigmentation and melasma, combine Glutathione Niacinamide (morning) + Tranexamic Acid Niacinamide (evening) with SPF50+ mineral mandatory. Strictly contraindicated during pregnancy and breastfeeding: all lines containing retinol (Liposome Retinol, Coenzyme Q10 Retinol, Mandelic Acid Retinol, Lactic Acid Retinol, Retinol Vit C Vit E, Spicule Retinol Shot 180) ».»
The BeautyDecoded application lets you scan any cosmetic product to visualize its suitability for your skin type and needs, based on INCI analysis - particularly useful for arbitrating among the 35+ APLB thematic lines according to your main objective (anti-spot, anti-aging, barrier restoration, anti-imperfections), your skin tolerance level, and your stage of cosmetic routine (preventive or corrective).
Information for educational purposes only, not a substitute for medical consultation. BeautyDecoded is an artificial intelligence cosmetic analysis application and is not a medical diagnostic tool. APLB is a South Korean K-beauty active-centric cosmetics brand - its products are not medical devices. This analysis is based on 111 APLB references algorithmically analyzed by BeautyDecoded, with 9 registered user reviews focused on the Glutathione Niacinamide line (a worldwide bestseller). Average sensitive skin score +1.56 (median +2.00) - absolute record observed on the BeautyDecoded panel, higher than the previous TIRTIR record (+0.12). Record sensitive skin score +3.55 (Hyaluronic Acid Ceramide HA B5 Ampoule Serum) - new BD absolute record, previous record Cica Care Serum TIRTIR at +3.25. Concentrations communicated on key formulations Niacinamide 20,000 ppm (2 %), Glutathione 1,000 ppm (0.1 %), Centella asiatica extract 29.2 %. Four patented technologies LIPO GLUTA NIAC CEN™ (liposomal encapsulation signature 31.3 %), Liposome (phospholipid encapsulation), Spicule (cosmetic microneedling via sea sponge spicules - Shot 180 retinol, Shot 260 niacinamide, Shot 300 collagen), Exosome (regenerative cell vesicles). Formative nuggets from the catalog (1) HA B5 Ceramide Ampoule Serum (+3.55 absolute BD record - reference for barrier restoration post-dermatological procedure, rosacea, stabilized atopic dermatitis), (2) Liposome Retinol LX Serum (anti-aging 88.4 + sensitive +1.05 - probably the best-tolerated cosmetic retinol observable), (3) Glutathione Niacinamide Ampoule Serum (worldwide K-beauty bestseller perfectly justified formally). Honest nuances reported in full analysis Glutathione Niacinamide Body Wash (-5.25, consistent with the detergent nature of a shower gel - to be used with a quick rinse without prolonged application) and Retinol Vitamin C Vitamin E Sunscreen (-2.20, consistent with a sunscreen containing retinol - a combination usually not recommended as it is photo-sensitizing; for sun use on sensitive skin, Glutathione Niacinamide Sunscreen -1.25 is preferable). SPF 50+ morning mandatory on all APLB routines incorporating a retinoid (documented photosensitization - entire retinoid class). Retinol precautions Gradual introduction mandatory (2 evenings/week × 4 weeks minimum), SPF 50+ morning mandatory, strictly contraindicated in pregnancy and breastfeeding like all retinoids (ANSM precautionary principle extended to all topical retinoids) - concerns all APLB lines containing retinol: Liposome Retinol LX, Coenzyme Q10 Retinol, Mandelic Acid Retinol, Lactic Acid Retinol, Retinol Vit C Vit E, Spicule Retinol Shot 180, and all references mentioning «Retinol» in the name. 48-hour patch test on forearm recommended before facial use for all new active ingredients on reactive skin. In the event of a skin reaction to a cosmetic, stop use immediately and consult a healthcare professional. For any skin condition that is chronic or resistant to cosmetic care after 2-3 months (moderate to severe acne, resistant melasma, active inflammatory rosacea, advanced photoaging, active eczema, psoriasis), dermatological consultation is a priority - APLB is a coherent cosmetic complement to medical care, not a substitute for it. This article does not constitute a commercial partnership with the APLB brand.