Brand reviews - BeautyDecoded analysis
Theramid.

Opinions Theramid - Doctor's analysis and BeautyDecoders' opinion.

Theramid is a line of active serums developed by NicheBeautyLab, positioned in the premium clinical skincare segment. The catalog is composed exclusively of serums - 10 references identified in the BeautyDecoded database, each targeting a specific problem with specifically documented active ingredients. The brand's central distinguishing feature is the transparency of the formulas' INCI information.

Author Dr Sylvain David
Expertise Independent cosmetic analysis
Products analyzed 10 serums
Compiled opinions 7 BeautyDecoded returns
95,2
Anti-âge max (Clinical Vitamin A - record-breaking BD base)
93,5
Rougeurs max (AZID - 5/5 out of 5 reviews, rosacea tolerance)
+2,5
Sensitive skin max (Lino-8 - no irritants detected)
10
Tested sera - exclusively active sera range

Analyse a Theramid product on your skin profile.

The BeautyDecoded application lets you scan any cosmetic product to visualize its suitability for your skin type and needs, based on INCI analysis - particularly useful for arbitrating between the 10 serums in the Theramid catalog according to your personal profile (Lino-8 sensitive skin / AZID rosacea / Clinical Vitamin A corrective anti-aging / Copper Peptide retinoid-free anti-aging / HAPCA Filler hydration) and for calibrating a protocol for the gradual introduction of a powerful retinoid like Clinical Vitamin A.

Application available on iOS and Android

An objectively serious active-centric approach - formative transparency as a brand signature.

L'detailed examination of the INCIs of the 10 Theramid serums highlights formulation rigor superior to the clean beauty premium market average. Several objective factors support this observation. About retinoids : three distinct serums targeting different levels of retinoid commitment - A Retinyl Retinoate (retinaldehyde + mild ester), Clinical Vitamin A (tri-retinoid HPR + Retinol + Retinal), Copper Peptide (anti-aging without retinoid). This stratification enables gradual clinical ramp-up. About peptides Copper Peptide specifically identifies the Copper Tripeptide-1 (GHK-Cu) in 6th position INCI - clinically documented anti-aging peptide reference (Pickart 2018). Derma-Peptides combines 5 different bioactive peptides identified one by one (Acetyl Hexapeptide-1, N-Prolyl Palmitoyl Tripeptide-56, Acetyl Tetrapeptide-2, Palmitoyl Tripeptide-38, Tripeptide-1) - sophisticated cosmetological stratification. About ceramides Ceramide Treatment identifies by name 5 different types (NG, NP, AP, AS, NS, EOP) - higher level of transparency than most marquess who make do with generic Ceramide NP. AZID also contains 5 ceramides in addition to azelaic acid. On anti-stain Even In serum combines tranexamic acid + arbutin + kojic acid + nonapeptide-1 + azelaic derivative + carnosine + lactobionic + mandelic acid - multi-mechanism anti-stain formulation unusual in the clean beauty segment.

01

Formulative transparency - higher than the segment average

Visit Theramid's first objective distinguishing feature is transparency on the exact nature of assets. Most of the marques ceramides on the market communicate «contains ceramides» without specifying either types or concentrations - a generic Ceramide NP at the bottom of the INCI list is enough to validate the communication. Theramid specifically identifies 5 different types of ceramide (NG, NP, AP, AS, NS, EOP) in Ceramide Treatment and AZID. each type targets a distinct biological function of epidermal intercellular cement (see dedicated biological table below). The same rigor applies to peptides: 5 bioactive peptides identified in Derma-Peptides, GHK-Cu mentioned by name in Copper Peptide with its precise INCI position. This transparency enables clinically informed INCI reading that most marquess make impossible through communication opacity. It's a good point to recognize objectively, which distinguishes Theramid from marques, which has a similar marketing positioning but lower formula transparency.

02

The price-arbitrage differential according to the value attributed to execution quality

Visit Theramid price positioning (~38 to 50 €/30 ml) is located well above the dermo-cosmetic references available on the market on comparable segments. For ceramides Ceramide Treatment Theramid ~50 € vs. CeraVe Moisturizing Cream ~€12/340 g (reference available with MVE Technology and independent published clinical data). For peptides Copper Peptide ~50 € vs. The Ordinary Buffet + Copper Peptides 1 % ~€30 (reported concentrations, published data). For azelaic acid 15 % AZID ~38 € vs Nooance Clarifying Care ~€35 (AA 15 % + BHA, independent data). The price differential must be weighed according to the value attributed to (1) the superior formulative transparency Theramid on the exact nature of the assets; (2) the cumulative ceramide diversity (5 types vs. 1-3 among competitors); (3) the global premium formulative quality with multi-asset stratification; (4) the BeautyDecoded user feedback (5/5 out of 5 reviews for AZID, 4.25/5 out of 2 reviews for C-Tetra E.F.), confirming the effectiveness of our flagship products. For a consumer whose budget favors accessibility with documented assets at communicated concentrations, The Ordinary, SVR or La Roche-Posay remain serious alternatives at much lower prices. For specific problems where Theramid is superior (AZID 15 % on rosacea with exceptional tolerance confirmed 5/5 out of 5 reviews), price arbitrage may tip in Theramid's favor.

Editorial reading

" Ceramides are one of the active ingredients I talk about most in my consultations.. Not because it's trendy - because it's biologically based. Reconstituting intercellular cement with the same molecules naturally present in the skin is the most rational approach to treating a deficient barrier. Among marques ceramides, Theramid stands out for its transparency. 5 ceramides identified by name in Ceramide Treatment, repeated in other references (AZID, HAPCA Filler). It's a good thing to recognize. BeautyDecoded analysis confirms this structural diagnosis: AZID is the leading formulative reference with redness score 93.5 exceptional, sensitive skin +0.1 (remarkable result for an active ingredient with 15 %, which is usually irritating), rated 5/5 out of 5 reviews - tolerance on rosacea is confirmed by BD users who report finally tolerating an AA 15 % after abandoning it with other marquess. Lino-8 is the tolerance nugget of the catalog Sensitive skin +2.5 catalog record, no irritants detected in INCI - for patients with sensitive skin, rosacea or post-procedure skin (laser, peel), Theramid serum should probably be prescribed first. Clinical Vitamin A is the most powerful cosmetic retinoid formulation in the catalog with anti-aging 95.2 Theramid catalog record and among the best BeautyDecoded anti-aging scores of all catalogs combined (in Retinol 0.3 % Typology, Retinal 0.2 % The Ordinary, Retinol 0.3 SkinCeuticals - all at 93.5). but reserved for retinoid-experienced profiles (≥ 6 months without irritation), Strictly contraindicated for reactive and rosaceous skin, and during pregnancy and breastfeeding. The price differential with accessible dermo-cosmetic references remains the main arbitration factor. - For consumers who value premium formulative transparency and sophisticated multi-active layering, Theramid offers a consistent level of quality; ; for consumers seeking the best asset-price ratio, More affordable alternatives exist (CeraVe for ceramides, The Ordinary for peptides, Nooance for azelaic acid). Three editorial recommendations : (1) for rosacea and azelaic acid 15 % with documented tolerance AZID is the reference in the catalog and one of the most effective anti-redness serums in the entire BD database; (2) for sensitive, rosaceous or post-procedure skin Lino-8 as first-line treatment (no irritants detected, sensitive skin +2.5 record); (3) for powerful corrective anti-aging in retinoid-savvy profiles Clinical Vitamin A in very gradual introduction (1 evening/week × 4 weeks, then 2 evenings, then 3), SPF 50+ morning mandatory, contraindicated for pregnancy and breast-feeding».»

Ceramide biology - why it's a serious asset.

Visit ceramides are the main lipids in epidermal intercellular cement - about 50 % of stratum corneum lipids. This cement holds the corneocytes together Cells are the bricks, lipids are the mortar. When ceramides decline (age, UV, aggressive detergents, atopic dermatitis), the consequences are direct : transepidermal dehydration, loss of barrier function, skin fragility. Mapping of the 5 ceramide types identified by Theramid and their specific biological roles.

Ceramide type Biochemical structure Role in the skin barrier
Ceramide 1 (EOS / EOP) Esterified fatty acid + sphingosine or phytosphingosine Bridge between lipid lamellae - barrier cohesion
Ceramide 3 (NP) Non-hydroxy fatty acid + phytosphingosine Hydration and skin suppleness
Ceramide 6-II (AP) Alpha-hydroxy fatty acid + phytosphingosine Regulation of desquamation and intercellular cohesion
Ceramide AS / NS Alpha-hydroxy / non-hydroxy + sphingosine variants Structural complements of the lipid matrix
Phytosphingosine Plant sphingoid base (precursor) Ceramide precursor, anti-inflammatory action
Source: Coderch L et al. Ceramides and skin function. Am J Clin Dermatol. 2003.
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Why is ceramide diversity a formulating advantage? Visit natural epidermal lipid matrix contains 9 different ceramide classes with specific complementary functions. Replenish this matrix with exogenous inputs is more effective when several types of ceramide are delivered simultaneously rather than a single isolated type. Most marques ceramides on the market are content with a Generic Ceramide NP in low INCI position - limited effectiveness. Theramid identifies 5 different types (NG, NP, AP, AS, NS, EOP) in Ceramide Treatment and AZID. this targeted diversity covers the majority of intercellular cement functions. Cross-project comparison : CeraVe Moisturizing Cream (~12 €/340 g - ceramides 1/3/6-II + MVE Technology + AH + niacinamide) offers 3 ceramides identified with larger independent clinical studies published ; Avene XeraCalm A.D. (~15 €/200 ml) offers biomimetic lipids + Cer-Omega + thermal extracts with specific positioning for documented atopic skin ; Byoma Gel-Cream (~€16/50 ml) offers a tri-ceramides + niacinamide + green tea with light gel-cream format. Theramid offers the highest diversity of ceramides in the segment, but at a significantly higher price..

What has changed in the perception of Theramid - updated vs. initial analysis.

This article updates a previous analysis published by BeautyDecoded on Theramid, with two notable differences that justify a revised overall conclusion.

📊
First, the BeautyDecoded database now includes all 10 Theramid serums algorithmically analyzed (compared with 2 previously). This extension enables a much more complete and nuanced reading of the catalog - it becomes possible to objectively map the range consistency across 7 clinical issues distinct (barrier, corrective anti-aging, hydration, radiance, anti-spot, rosacea, preventive anti-aging).

Second, detailed examination of INCIs reveals a higher level of formulative transparency than previous analysis suggested. The brand specifically identifies its ceramides (5 types in Ceramide Treatment and AZID), peptides (5 in Copper Peptide and Derma-Peptides), and retinoids (HPR + Retinol + Retinal in Clinical Vitamin A). It's a level of rigor that exceeds the average in the clean beauty premium segment, and one that should be recognized objectively..

The previous conclusion («AZID is the positive exception, the rest lack rigor») has aged with the enrichment of the BeautyDecoded database. The updated conclusion is more nuanced : Theramid is a serious range of documented active serums, with a above-average formulative transparency, including AZID remains the benchmark and several other references (Even In, Lino-8, HAPCA Filler, Copper Peptide) are relevant options for different skin profiles. The price differential with accessible dermo-cosmetic references remains a factor to be arbitrated. according to the value attributed to premium formulative performance.

The ten Theramid serums, at a glance.

Sorted by decreasingly sensitive skin score. AZID and Lino-8 are the two references of first choice for sensitive or reactive skin. Clinical Vitamin A is the most powerful anti-ageing option but strictly contraindicated for sensitive skin (sensitive skin score -6.9, redness score -216.8 - the most negative in the catalog).

Product Target Sensitive skin Key score
Lino-8Soothing barrier+2,50No irritants detected - Redness 76.5 - No opinion BD
HAPCA FillerDeep hydration+0,50Triple AH + ceramide NG - No BD Reviews
AZID - Azelaic acid 15 %Redness / acne+0,10Redness 93.5 - Imperf 88.4 - Spots 88.4 - 5/5 out of 5 reviews
C-Tetra E.F. (derived vitamin C)Stains / sheen0,00Anti-ageing 83.3 - Spots 86.7 - 4.25/5 out of 2 reviews
Ceramide TreatmentBarrier (5 ceramides)-0,205 named ceramides + ectoin
Copper PeptideGlobal anti-aging-0,50GHK-Cu + bifida ferment + 4 peptides - Anti-ageing 86.7
Derma-PeptidesPreventive anti-aging-0,505 identified bioactive peptides - Anti-ageing 76.5
Even InMulti-mechanism anti-tasking-0,60Tranexamic acid + arbutin + kojic acid - Redness 91.8
A Retinyl RetinoateMild retinoid anti-aging-1,20Retinal + retinyl retinoate - Anti-ageing 86.7
Clinical Vitamin APowerful corrective anti-aging-6,90HPR + Retinol + Retinal - Anti-ageing 95.2 record
Family 01

AZID - the flagship formulative reference in the Theramid catalog

L'AZID is the Theramid product that convinces doctors without reservation : documented active ingredient (azelaic acid 15 %), indicated concentration, hybrid formulation enriched with 5 ceramides + carnosine, exceptional redness score (93.5), optimal sensitive skin score (+0.1) on a 15 % active ingredient that usually irritates, BeautyDecoded rating 5/5 out of 5 reviews - the best in the Theramid catalog with a significant volume of reviews.

Azelaic acid serum 15 % + 5 ceramides - redness / acne

AZID - Azelaic acid 15 %

★★★★★ 5,00/5 (5 reviews - leading formulative catalog reference) ~38 € / 30 ml
TOP catalog Theramid - AA 15 % tolerated on sensitive skin +0.1 - redness 93.5 exceptional - 5/5 out of 5 reviews

Azelaic acid 15 % - concentration corresponding to the clinically validated therapeutic threshold (15 % in cosmetics, 20 % in prescribed medical formulations). Hybrid formulation enriched with 5 identified ceramides (NP, EOP, NS, AS, AP), carnosine (antioxidant and anti-glycation), oat extract (Avena sativa) and acetyl tetrapeptide-2. This construction mechanically explains the higher tolerance observed. Ceramides support the barrier during the action of azelaic acid.

Scores BeautyDecoded
Dry skin
77
Oily skin
91
Normal to dry skin
91
Normal to oily skin
91
Sensitive skin
+0,1
Redness / Imperf
93,5 / 88,4
✅ Sensitivity verdict Suitable for sensitive skin (score: +0.1). Remarkable result on AA 15 % which usually irritates. Rosacea tolerance confirmed by 5 reviews.
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Why is AA 15 % tolerated on sensitive skin here? Azelaic acid at 15 % in cosmetics has a reputation for irritation documented on reactive skin: therapeutic concentration often provokes Tingling, reactional redness and transient burning application on sensitive or rosaceous skin. AZID Theramid's +0.1 sensitive skin score at this concentration is a remarkable formulatory result.. Three factors explain this superior tolerance : (1) the 5 ceramides identified in the formula (NP, EOP, NS, AS, AP) simultaneously reinforce the hydrolipidic barrier during the action of AA -. the preserved barrier limits excessive asset penetration, (2) carnosine as an antioxidant and anti-glycation agent modulates cellular inflammatory response, (3) oat extract (Avena sativa) provides a documented soothing effect. The 5 BD opinions clinically confirm this formulatory diagnosis : several users report finally tolerating an AA 15 % after having abandoned it in others marques due to burning and tingling.
Source: Draelos ZD et al. Azelaic acid 15% gel in the treatment of rosacea. J Drugs Dermatol. 2006.
" AZID is the Theramid product that convinces doctors without reservation : documented active ingredient (azelaic acid 15 %), indicated concentration, addition of ceramides + carnosine to support the barrier, exceptional redness score (93.5), optimal sensitivity score (+0.1). BeautyDecoded rating (5/5 out of 5 reviews) confirms superior tolerance and efficacy on rosacea skin compared to other AA 15 % formulations on the market.. Cross-project comparison : Nooance Clarifying Care (~35 €, AA 15 % + BHA, independent data - AA segment benchmark for oily skin); ; Azelaic acid 10 % + Bamboo Typology (~25.50 €, FLOP catalog Typology - pipette failure documented but active relevant imperfections 90.1); ; Azelaic Acid Suspension 10 % The Ordinary (FLOP unique in The Ordinary catalog - silicone vehicle unsuitable for oily skin, recurrent linting documented). AZID Theramid is distinguished by its combination of therapeutic concentration (15 %) + tolerance for sensitive skin (+0.1) + ceramide base. - unique positioning in the AA premium segment.»
User feedback (5 reviews - rosacea tolerance confirmed vs other AA 15 %)
★★★★★«Vascular and inflammatory rosacea. After burning and tingling with other marques to 15 % AA, opted for 10 % formulations. AZID Theramid 15 % is finally tolerated without these discomforts.»
★★★★★«Hyper-sensitive oily skin with rosacea: helps me enormously. My discovery of the year.»
★★★★★«Very pleasant texture, absorbs well, does not fluff. Very well tolerated by my sensitive skin. Skin is refined and less red.»
★★★★★«Top serum. Blends very well into the skin without irritating. A little expensive.»
★★★★★«Not too effective on my skin after 1 month, but texture less dry than other azelaic acid products.»
Verdict - TOP Theramid catalog - Rated 5/5 out of 5 reviews. Redness 93.5 exceptional + blemishes 88.4 + spots 88.4. Sensitive skin +0.1 record on AA 15 %. Rosacea tolerance confirmed vs. other AA 15 % formulations abandoned by users. Hybrid formulation 5 ceramides + carnosine + oats which supports the barrier during AA action.
Family 02

Barrier and hydration - Lino-8, Ceramide Treatment, HAPCA Filler

Three barrier and hydration serums with excellent tolerance profiles. Lino-8 is the tolerance nugget in the catalog : sensitive skin +2.5 - record score, no irritants detected in INCI. Ceramide Treatment is the’formulative expression of the Theramid signature with 5 ceramides identified by name. HAPCA Filler combine 3 forms of hyaluronic acid + ceramide NG + sphingolipids.

Soothing barrier serum - linoleic acid + Q10 + panthenol

Lino-8

- N/A (no BD review - sensitive skin score +2.5 catalog record) ~45 € / 30 ml
TOP tolerance catalog - sensitive skin +2.5 record - NO irritants detected in INCI

Barrier formulation built around panthenol (provitamin B5) in 2nd position INCI, linoleic acid in 3rd position (omega-6 essential fatty acid), precursor of endogenous ceramides), avocado oil, Saccharomyces ferment (fermented yeast rich in beta-glucans), phytonadione epoxide (vitamin K1), ubiquinone (Q10) mitochondrial antioxidant, and linolenic acid (omega-3). Sensitive skin score +2.5 - the highest in the Theramid catalog. NO irritants detected in INCI.

Scores BeautyDecoded
Dry skin
84
Oily skin
49
Normal to dry skin
91
Normal to oily skin
87,5
Sensitive skin
+2,5
Redness
76,5
✅ Sensitivity verdict Suitable for sensitive skin (score: +2.5 - catalog record). No irritants detected.
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Consistent biochemical strategy - provide lipid precursors rather than exogenous ceramides. Lino-8 adopts a complementary barrier strategy to Ceramide Treatment. Where Ceramide Treatment directly provides the final ceramides, the Lino-8 provides essential fatty acid precursors (omega-6 linoleic acid, omega-3 linolenic acid) which are converted into endogenous ceramides by the skin itself via the sphingolipid biosynthetic pathway. This strategy offers three advantages : (1) maximum biocompatibility - the skin uses its own enzymes to synthesize the ceramides it needs according to its physiological state (2) no cosmetic irritants - essential fatty acids and panthenol are among the best-tolerated active ingredients in cosmetology, (3) intrinsic anti-inflammatory action linoleic acid. For sensitive, rosacea-prone, atopic or post-procedure (laser, peel) skin, Theramid serum should probably be prescribed first. Limit : score imperfections -38.2 - oil-rich formula to be avoided on acne-prone skin.
" Lino-8 is the tolerance nugget in the Theramid catalog : no irritants detected, sensitive skin score +2.5 (catalog record), redness score 76.5. For patients with sensitive skin, rosacea or post-procedure skin (laser, peel), Theramid serum should probably be prescribed first. The biochemical strategy is consistent : providing ceramide precursor essential fatty acids is the complementary approach to direct ceramide intake. For skins with imperfections, the negative imperfections score (-38.2) reflects the high oil content - find out more. Compare with Centella Ampoule Skin1004 (~€16, 35 BD reviews, anti-aging 91.8, sensitive skin +2.25) - Skin1004 more affordable and better Q/P in the soothing segment; ; Bariéderm-Cica Uriage Serum (~€30, 6 BD reviews, sensitive skin +1.75) - Uriage offers specific post-procedure thermal water isotonicity.»
Verdict - TOP tolerance catalog Theramid - Sensitive skin +2.5 record. NO irritants detected in INCI. Endogenous ceramide precursor essential fatty acid strategy. Excellent option for sensitive, rosaceous and post-procedure skin. Blemish score -38.2 - avoid acne-prone skin. No BD user reviews yet for practical validation.
Barrier serum 5 identified ceramides + ectoin

Ceramide Treatment

- N/A (no opinion BD - signature formulative Theramid) ~50 € / 30 ml
Formulative signature - 5 ceramides identified (NG, NP, AP, AS, NS, EOP) - superior market diversity

The the central formative element in Theramid's positioning a barrier serum with 5 specific ceramides named in the INCI - Ceramide NG (7th position), Ceramide NP (11th), Ceramide AP (12th), Ceramide AS (13th), Ceramide NS (14th), Ceramide EOP (15th). This targeted diversity covers the major types of epidermal ceramides. Presence of ectoin (natural protective osmolyte) and glycine soy (soy lecithin).

Scores BeautyDecoded
Dry skin
43,4
Oily skin
84
Normal to dry skin
46,9
Normal to oily skin
91
Sensitive skin
-0,2
Anti-aging / Redness
56,1 / 27,2
⚠ Sensitivity verdict Slight caution (score: -0.2). Presence of alcohol reported - dose according to profile.
" Ceramide Treatment is the formulative expression of the Theramid signature.. The diversity of ceramides identified (5 types) is objectively superior to the market norm. - a favorable point to recognize. For a serious barrier routine for oily-combination skin, This is a relevant option (normal to oily skin score 91, oily skin 84). For dry to very dry skin, moderate dry skin scores (43.4) suggest that a more emollient cream format would still be preferable. - CeraVe Moisturizing Cream at €12 for 340 g remains a reference accessible with MVE Technology and more voluminous published clinical data. The price differential must be weighed against the value attributed to cumulative ceramide diversity.. Important note : concentrations remain undisclosed - the low position of ceramides in the INCI list (7th to 15th) suggests cumulative concentrations that may be significant without being quantified».»
Verdict - Signature formulative Theramid - No BD Reviews. 5 ceramides identified (superior market diversity). Normal to oily skin score 91 optimal. Dry to very dry skin: prefer cream format (CeraVe Moisturizing Cream). Ceramide concentrations not communicated. Price differential vs. CeraVe to be arbitrated according to cumulative diversity value.
Triple AH moisturizing serum + NG ceramide + sphingolipids

HAPCA Filler

- N/A (no opinion BD - triple AH + ceramide NG) ~45 € / 30 ml
Deep hydration - triple AH + ceramide NG + beta-glucan - sensitive skin +0.5

Combines three forms of hyaluronic acid (hydrolyzed HA, sodium acetylated hyaluronate, sodium hyaluronate implicite) with sphingolipids, phospholipids, ceramide NG and beta-glucan. Sensitive skin score +0.5 - positive. No irritants detected in INCI.

✅ Sensitivity verdict Suitable for sensitive skin (score: +0.5). No irritants detected.
" HAPCA Filler is the deep moisturizing benchmark in the Theramid catalog. - 3 forms of HA with different molecular weights allow multi-level hydration (high weight = surface tensor film, low weight = epidermal penetration). The addition of NG ceramide and sphingolipids supports the barrier during hydration. For sensitive dry to dehydrated skin, it's a relevant option. Compare with Polyglutamic acid 3 % + Typology algae (DÉCOUVERTE BD, €28, new-generation PGA humectant superior to AH - rated 5/5 out of 2 reviews), Serum AH 3 % + B5 Typology (4.25/5 out of 2 BD reviews, sensitive skin +1.5), Hyaluronic Acid 2 % + B5 The Ordinary (~€7.90, similar formula cheaper). »
Verdict - Deep hydration - No opinion BD. Triple AH + NG ceramide + beta-glucan + sphingolipids. Sensitive skin +0.5 positive. No irritants detected. No BD user reviews yet for practical validation.
Family 03

Corrective anti-aging - Clinical Vitamin A, A Retinyl Retinoate, Copper Peptide, Derma-Peptides

Four anti-aging serums with progressive power stratification. Clinical Vitamin A is the most powerful cosmetic retinoid formulation in the catalog with anti-aging 95.2 record - reserved for retinoid-resistant skin. A Retinyl Retinoate is the’gentle retinoid introduction (retinaldehyde + retinyl retinoate ester). Copper Peptide and Derma-Peptides offer a retinoid-free anti-aging alternative compatible with contraindicated profiles (pregnancy, breast-feeding, intolerance).

Powerful tri-retinoid serum HPR + Retinol + Retinal

Clinical Vitamin A

- N/A (no opinion BD - anti-âge 95.2 record catalog) ~50 € / 30 ml
Anti-ageing 95.2 record catalog - tri-retinoid HPR + Retinol + Retinal - contraindicated for sensitive skin

High-level tri-retinoid formulation combining three complementary molecules : Hydroxypinacolone Retinoate (HPR) - aka granactive retinoid, retinoic acid ester that binds directly to RAR receptors without the need for prior enzymatic conversion, unlike retinol, which requires two conversions. 11th INCI position. Also present Retinol (12th position) and Retinal (retinaldehyde) (13th position) - or a combination of the three major cosmetic retinoids. Anti-ageing score 95.2 - the highest in the Theramid catalog and among BeautyDecoded's top anti-aging scores across all catalogs.

Scores BeautyDecoded
Dry skin
91
Oily skin
59,5
Normal to dry skin
98
Normal to oily skin
98
Sensitive skin
-6,9
Anti-ageing / Spots
95,2 / 93,5
❌ Sensitivity verdict Not suitable for sensitive skin (score: -6.9). Redness score -216.8 - the most negative in the catalog.
⚠️
Strict precautions - potent tri-retinoid formulation. Sensitive skin score -6.9 and redness score -216.8 (the most negative in the catalog) - formulation strictly contraindicated for reactive, rosaceous or atopic skin, or during pregnancy or breastfeeding.. HPR (hydroxypinacolone retinoate) is a retinoic acid ester that binds directly to RAR receptors without requiring enzymatic conversion - is the most directly bioactive cosmetic form available over the counter. Combined with retinol and retinaldehyde, the formulation combines three simultaneous retinoid activation pathways. Mandatory introduction protocol : 1 evening/week for 4 weeks, then 2 evenings/week for 4 weeks, then 3-4 evenings/week depending on tolerance. SPF 50+ morning mandatory for the duration of use and 4 weeks after discontinuation. Strictly contraindicated during pregnancy and breast-feeding - all retinoids are teratogenic as a precautionary measure. Never combine with AHA/BHA on the same evening. Skin purging phenomenon possible at start-up (transient acne accentuation) - an expected reaction, not a permanent adverse effect.
Source: Sorg O et al. Topical retinaldehyde: a novel use for an old molecule. Dermatology. 1999.
" Clinical Vitamin A is probably the most powerful cosmetic retinoid formulation in the Theramid catalog., and one of the most comprehensive in the clean beauty premium segment. For consumers already used to retinoids (use ≥ 6 months of retinol at medium concentration without irritation), it's a relevant option for taking your business to the next level. For first-time users or reactive skin, strictly avoid - formative richness (HPR + Retinol + Retinal simultaneously) mechanically generates a very unfavorable algorithmic tolerance. Cross-project comparison : anti-aging 95.2 vs anti-aging 93.5 at Retinol 0.3 % Typology (~€29.90, 5-ingredient formula, rated 5/5 out of 3 BD reviews), Retinal 0.2 % The Ordinary (~€14.90, retinaldehyde - even more effective than retinol), Retinol 0.3 SkinCeuticals (~70-85 €, reference formula). Clinical Vitamin A stands at 95.2 - slightly above the usual ceiling of 93.5 thanks to the combination of 3 retinoids. For first-time Theramid users : prefer’A Retinyl Retinoate (softer introduction, sensitive skin -1.2 vs -6.9)».»
Verdict - Anti-ageing 95.2 record catalog - No BD review. Tri-retinoid HPR + Retinol + Retinal. Strictly contraindicated for sensitive, rosaceous and atopic skin, pregnancy and breast-feeding.. For retinoid-resistant profiles ≥ 6 months. Mandatory gradual introduction (1 evening/week × 4 weeks). SPF 50+ morning mandatory.
Mild retinoid serum - retinaldehyde + retinyl retinoate ester

A Retinyl Retinoate

- N/A (no opinion BD - soft retinoid introduction) ~45 € / 30 ml
Gentle introduction retinoid - anti-ageing 86.7 - sensitive skin -1.2 more tolerant than Clinical Vitamin A

Combination retinaldehyde + retinyl retinoate (mild ester form) + sodium retinoyl hyaluronate. Anti-ageing score 86.7 - solid. Sensitive skin score -1.2 - significantly more tolerant than Clinical Vitamin A (-6.9). A gentle introduction to retinoids.

⚠ Sensitivity verdict Slight caution recommended (score: -1.2). Gradual introduction recommended.
" A Retinyl Retinoate is the mild retinoid introduction to the Theramid catalog. - retinyl retinoate is a retinol ester that is much more stable and better tolerated than pure retinol., while the retinaldehyde offers intermediate efficacy between retinol and retinoic acid. Anti-ageing score 86.7 + sensitive skin -1.2: «first-time retinoid user» positioning». Compare with Retinal 0.2 % The Ordinary (~14.90 €, pure retinaldehyde, anti-aging 93.5) - The Ordinary cheaper and better anti-aging score but without the signature Theramid combined. For a first-time user looking to start a retinoid without the maximum potency, this is a coherent option.»
Verdict - Soft retinoid introduction - No opinion BD. Anti-ageing 86.7 solid. Sensitive skin -1.2 more tolerant than Clinical Vitamin A. Retinaldehyde + retinyl retinoate ester. Suitable for first-time retinoid users. Retinol precautions applicable (SPF 50+ morning, not recommended for pregnant women).
Serum copper peptide GHK-Cu + 4 peptides + bifida ferment

Copper Peptide

- N/A (no BD review - retinoid-free anti-aging alternative) ~50 € / 30 ml
Anti-ageing 86.7 retinoid-free - GHK-Cu Pickart documented - alternative pregnancy / breastfeeding / intolerance

Serum focused on Copper Tripeptide-1 (GHK-Cu) in 6th position INCI - the best-documented anti-aging copper peptide in cosmetology, studied for its effects on collagen synthesis, extracellular matrix remodeling and tissue repair (Pickart 2018). Complementary presence from bifida ferment lysate (topical probiotic), acetyl tetrapeptide-2, trifluoroacetyl tripeptide-2 (firming peptide), sh-oligopeptide-1 (biotech EGF) and sodium hyaluronate.

Scores BeautyDecoded
Dry skin
60,9
Oily skin
84
Normal to dry skin
81,9
Normal to oily skin
91
Sensitive skin
-0,5
Anti-aging
86,7
⚠ Sensitivity verdict Slight caution recommended (score: -0.5). Lactic acid in low INCI position.
Source: Pickart L et al. The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions. Biomedicines. 2018.
" Copper Peptide is a serious anti-aging option for profiles that cannot tolerate retinoids or are looking for a complementary alternative.. GHK-Cu remains one of the most clinically documented anti-aging peptides. Combined with other bioactive peptides and probiotic bifida ferment lysate, the result is a coherent formulation.. For a complete anti-aging protocol, it's a relevant option as a daytime routine or alternating nightly with a retinoid. Cross-project comparison : Multi-Peptides + Copper 1 % The Ordinary (~€16.60, anti-aging 88.4 - equivalent alternative 3× cheaper, transparent comparison documented in The Ordinary BD reviews); ; Nooance Copper Peptide Serum (~55 € - equivalent to Multi-Peptides + Copper The Ordinary according to BD users). The Theramid Copper Peptide vs. The Ordinary Multi-Peptides + Copper price differential (€50 vs. €16.60) must be weighed against the value attributed to overall formulative performance.. Compatible with pregnancy and breastfeeding (no retinoids)».»
Verdict - Anti-ageing 86.7 without retinoids - No opinion BD. GHK-Cu Pickart documented + 4 peptides + bifida ferment. Alternative pregnancy / breastfeeding / retinoid intolerance. Significant price differential vs. The Ordinary Multi-Peptides + Copper. Sensitive skin -0.5 slight caution.
Preventive anti-aging serum 5 identified bioactive peptides

Derma-Peptides

- N/A (no BD review - anti-aging preventive 25-35 years) ~45 € / 30 ml
Preventive anti-aging 76.5 - 5 identified bioactive peptides - sophisticated cosmetological stratification

Sophisticated peptide layering combining : Acetyl Hexapeptide-1, N-Prolyl Palmitoyl Tripeptide-56 Acetate (peptide stimulating collagen synthesis), Acetyl Tetrapeptide-2, Palmitoyl Tripeptide-38 («matrikine» signaling peptide, simultaneously stimulates collagen, elastin, HA and fibronectin), and Tripeptide-1. This combination targets the main skin matrix remodelling pathways without the need for a retinoid.. Consistent 76.5 anti-aging score.

⚠ Sensitivity verdict Slight caution recommended (score: -0.5).
" Derma-Peptides is a relevant option for preventive anti-aging profiles (ages 25-35) or as an alternative to a retinoid.. Peptide layering is cosmetically sophisticated - this is exactly the type of formulation found on The Ordinary Buffet or Matrixyl 10% + HA at a much lower price.. For a consumer who values a premium formulative experience and quality of execution, this makes sense.. For consumers looking for the best asset/price ratio, there are more affordable alternatives.. Compatible with pregnancy and breastfeeding (no retinoids)».»
Verdict - Preventive anti-aging - No opinion BD. 5 bioactive peptides identified (sophisticated stratification). Anti-ageing 76.5. Sensitive skin -0.5. Significantly cheaper alternative to The Ordinary Buffet or Matrixyl 10% + HA. Pregnancy-compatible.
Family 04

Anti-spot and radiance - C-Tetra E.F. and Even In multi-mechanisms

Two complementary anti-spot serums. C-Tetra E.F. (4.25/5 out of 2 comic book reviews) uses 3 stable vitamin C derivatives + ferulic acid - vitamin C tolerant for sensitive skin. Even In offers a multi-mechanism anti-spot formulation unusual in the clean beauty segment with tranexamic acid + arbutin + kojic acid + nonapeptide-1 + azelaic derivative - complete tri-action profile (spots 86.7 + redness 91.8 + anti-aging 66.3).

Derived vitamin C serum - 3 stable derivatives + ferulic acid

C-Tetra E.F. (derived vitamin C)

★★★★ 4,25/5 (2 reviews - vitamin C tolerant sensitive skin 0) ~42 € / 30 ml
Tolerant vitamin C - sensitive skin 0 - 3 stable derivatives + potentiating ferulic acid

Formulation based on three stable vitamin C derivatives : ascorbyl tetraisopalmitate (THDA) in 2nd INCI position (lipophilic derivative, epidermal penetration without acid pH), ascorbyl glucoside in 4th position (water-soluble glycoside derivative), and ascorbyl methylsilanol pectinate. Remarkable presence of ferulic acid - antioxidant documented to stabilize vitamin C and potentiate its anti-free radical effect (Lin 2005).

Scores BeautyDecoded
Dry skin
91
Oily skin
63
Normal to dry skin
91
Normal to oily skin
70
Sensitive skin
0
Anti-ageing / Spots
83,3 / 86,7
✅ Sensitivity verdict Suitable for sensitive skin (score: 0). No irritants detected in INCI.
🍊
Ferulic acid - antioxidant that stabilizes and potentiates vitamin C. Ferulic acid is a documented natural antioxidant for stabilize vitamin C and enhance its anti-free radical effect (Lin 2005). Mechanism it protects vitamin C from oxidation (which converts AA into brown, inactive dehydroascorbic acid) and increases formula stability. The combination of vitamin C + ferulic acid + vitamin E is the CE Ferulic SkinCeuticals reference antioxidant combination (pure ascorbic acid 15 % + vit E + ferulic acid 0.5 %, ~180 €). C-Tetra E.F. Theramid features this combination with stable vitamin C derivatives more tolerant of sensitive skin which cannot tolerate pure ascorbic acid at acidic pH. More modest bioavailability than pure L-ascorbic acid at 10-15 % at pH 3 (clinical reference) - derivatives require cutaneous enzymatic conversion to become active. Blemish score 86.7 and anti-ageing score 83.3 reflect strong preventive antioxidant efficacy rather than a spectacular corrective effect.
Source: Lin FH et al. Ferulic acid stabilizes a solution of vitamins C and E, doubling its photoprotection of skin. J Invest Dermatol. 2005.
" C-Tetra E.F. is a well-constructed vitamin C serum with a trio of stable derivatives and potentiating ferulic acid. - a good option for sensitive skin that cannot tolerate pure ascorbic acid at low pH levels. Blemish score 86.7 and anti-ageing score 83.3 reflect solid preventive efficacy rather than a spectacular corrective effect. À 42 €/30 ml, it's a premium positioning comparable to Paula's Choice C15 Super Booster (pH-calibrated pure ascorbic acid, ~55 €) or with vitamin C dermo-cosmetics references (SVR Ampoule C, La Roche-Posay Pure Vitamin C 10, Vitamine C 11 % Typology at €12.50). The odor reported in the notices is characteristic of lipophilic ascorbic acid derivatives. in partial oxidation - to be aware of at the time of purchase without constituting a formal defect. »
User feedback (2 reviews - vitamin C tolerant sensitive skin documented)
★★★★«Very well tolerated by my sensitive skin. No spectacular effects or extra glow. I use it for prevention.»
★★★★«Very good product derived from vitamin C. Beware of the very strong smell. Still being tested.»
Verdict - Tolerant vitamin C derivative - Rated 4.25/5 out of 2 reviews. Anti-ageing 83.3 + Blemishes 86.7 + Sensitive skin 0. 3 stable derivatives + potentiating ferulic acid. Preventive rather than spectacularly corrective. Characteristic odor of AA esters - to know when purchasing. 2 insufficient opinions for robust conclusion.
Multi-mechanism anti-spot serum - tranexamic acid + arbutin + kojic acid

Even In - Multi-mechanism anti-tasker

- N/A (no BD notice - complete tri-action profile) ~50 € / 30 ml
Complete tri-action profile - spots 86.7 + redness 91.8 + anti-aging 66.3 - unusual multi-mechanisms

Multi-mechanism anti-stain formulation unusual in the clean beauty segment. Combination of : tranexamic acid in 4th INCI position (plasmin inhibitor, documented action on melasma - Taraz 2017), arbutin and kojic acid (tyrosinase inhibitors), nonapeptide-1 (anti-pigment peptide), potassium azeloyl diglycinate (water-soluble derivative of azelaic acid), carnosine (anti-glycation), licorice extract anti-inflammatory and anti-pigmentary, lactobionic acid (PHA gentle exfoliant) and mandelic acid (AHA exfoliant). This multi-target stratification explains the tri-action profile.

Scores BeautyDecoded
Dry skin
91
Oily skin
84
Normal to dry skin
91
Normal to oily skin
91
Sensitive skin
-0,6
Redness / Spots
91,8 / 86,7
⚠ Sensitivity verdict Slight caution recommended (score: -0.6). Patch test recommended due to formulative complexity.
Source: Taraz M et al. Tranexamic acid in treatment of melasma: a comprehensive review. J Cosmet Dermatol. 2017.
" Even In is probably the second most convincing Theramid product after AZID. For consumers looking for a serious anti-spot serum with a multi-mechanism approach, this is a relevant option.. Tranexamic acid in cosmetics remains an emerging active ingredient with solid clinical data on melasma - its use in cosmetic concentrations deserves to be reported. Patch test recommended before regular use due to complexity of ingredients. Spot score 86.7, consistent with a 6-8 week course of treatment as part of a daily or twice-daily routine. Cross-project comparison : Liftactiv Sérum B3 Vichy (~35 €, stains 95,2 record any BD base - 6 anti-melanogenesis actives at 3 levels, niacinamide 5 % + tranexamic acid + glycolic 3,5 % + stabilized vit C + peptides + rice protein); ; Mela B3 La Roche-Posay (~32 €, stains 90.1 - niacinamide + tranexamic acid without AHA); ; Tranexamic acid 5 % + Tetrapeptide Typology (DISCOVERY BD, spots 79.9 + redness 91.8, sensitive skin 0). At €50, Even In Theramid is positioned at the high end of the segment, but with a more complete multi-mechanism profile than its competitors.. »
Verdict - Complete tri-action profile - No opinion BD. Spots 86.7 + Redness 91.8 + Anti-ageing 66.3. Tranexamic acid + arbutin + kojic + nonapeptide-1 + azelaic derivative. Unusual multi-mechanism clean beauty segment. Test patch recommended. Price differential vs Liftactiv B3 Vichy (~€35, stains 95.2 record) to arbitrate.

Theramid vs. established references - objective comparison of comparable segments.

Comparison of Theramid positioning with established references on comparable segments : ceramides (CeraVe, Avène, Byoma), azelaic acid (Nooance), retinoid (The Ordinary), copper peptides (The Ordinary).

Brand / Product Approach Price Clinical evidence
CeraVe Moisturizing Cream Ceramides 1/3/6-II + MVE 24h + AH + niacinamide ~12 € / 340 g Very solid - published independent studies
Avene XeraCalm A.D. Biomimetic lipids + thermal extracts + ecobioline ~15 € / 200 ml Solid - documented atopic skin
Byoma Gel-Cream Tri-ceramides + niacinamide + green tea ~16 € / 50 ml Correct - verifiable claims
Theramid Ceramide Treatment 5 ceramides identified (NG, NP, AP, AS, NS, EOP) + ectoin ~50 € Limited - in-house studies only
Theramid AZID AA 15 % + 5 ceramides + carnosine + oats - indicated concentration ~38 € / 30 ml Documented + assets 5/5 out of 5 comic book reviews
Theramid Clinical Vitamin A HPR + Retinol + Retinal - rare tri-retinoid combination ~50 € Documented active ingredients - not suitable for sensitive skin
Theramid Copper Peptide GHK-Cu (Pickart) + bifida ferment + 4 peptides ~50 € Documented assets Pickart 2018
Nooance Clarifying Care AA 15 % + BHA - rosacea formulation ~35 € Independent data
The Ordinary Multi-Peptides + Copper 1 % Peptides + GHK-Cu - reported concentrations ~16,60 € Indicated concentrations, anti-aging 88.4 BD
⚖️
Synthetic reading - arbitration according to priority criteria. Theramid positions itself in a premium clean clinical segment with an objectively serious active-centric approach - named active ingredients, ceramide types identified, sophisticated peptide stratifications. The price differential with established benchmarks (CeraVe, Avène, The Ordinary) must be weighed against the value attributed to : (1) Theramid's superior formula transparency the exact nature of the assets; (2) the diversity of accumulated ceramides ; (3) global premium formulative quality. For AZID and C-Tetra E.F.the BeautyDecoded user feedback (5/5 out of 5 reviews, 4.25/5 out of 2 reviews) confirm the effectiveness felt. For budget-priority profiles The Ordinary, SVR or La Roche-Posay remain serious alternatives. For profiles that value premium formative experience Theramid offers a consistent level of quality.

Five Theramid routines according to skin profile.

Articulation of Theramid serums according to five main user profiles. SPF 50+ morning mandatory on all routines incorporating retinoids (A Retinyl Retinoate, Clinical Vitamin A) or AHA/PHA (Even In).

Skin profile Morning Evening
Sensitive / reactive / rosacea skin Lino-8 (+2.5 sensitive, no irritants) → barrier cream → SPF modern filters AZID (+0.1 sensitive, redness 93.5) 2-3 evenings/wk alternating with Lino-8 or HAPCA Filler
Dry / dehydrated skin HAPCA Filler (+0.5 sensitive, triple AH + NG ceramide) or Lino-8 → cream → SPF Ceramide Treatment or C-Tetra E.F. according to priority - A Retinyl Retinoate 1-2 evenings/week if anti-aging
Oily skin / imperfections / mild rosacea AZID (91 oily skin, 88.4 blemishes) → light cream → non-comedogenic SPF AZID alternates with Even In if pigmentation is a concern
Corrective anti-ageing 35+ (resistant skin with retinoids) C-Tetra E.F. or Copper Peptide alternating weekly → cream → SPF 50+ mandatory Clinical Vitamin A gradual introduction (1 evening/week × 4 weeks, then 2, then 3) - Ceramide Treatment retinoid-free nights
Preventive anti-aging 25-35 years C-Tetra E.F. → moisturizing cream → SPF (main preventive anti-aging gesture) Derma-Peptides or A Retinyl Retinoate 2-3 evenings/week + Ceramide Treatment the other evenings
⚠️
Retinoid precautions (Clinical Vitamin A, A Retinyl Retinoate). Mandatory phased introduction 1 evening/week for a minimum of 4 weeks, then 2 evenings/week for 4 weeks, then 3-4 evenings/week depending on tolerance. SPF 50+ morning mandatory for the duration of use and 4 weeks after discontinuation. Strictly contraindicated during pregnancy and breast-feeding - all retinoids are teratogenic as a precautionary measure. Never combine with AHA/BHA on the same evening (so no Clinical Vitamin A + Even In on the same evening - alternate). Skin purging phenomenon possible at startup. For pregnancy and breastfeeding profiles : prefer Copper Peptide (anti-aging 86.7 without retinoids) or Derma-Peptides (anti-aging 76.5 without retinoids).

Is Theramid made for you?

Table of user profiles with recommendations based on the 10 serums analyzed in BeautyDecoded.

User profile Theramid benefits Recommended product
Rosacea with intolerance AA 15 % in others marquesMaximal - hybrid formulation 5 ceramides + AA 15 %AZID (sensitive skin +0.1, redness 93.5, 5/5 out of 5 reviews)
Sensitive skin / post-laser procedure / atopic skinStrong - sensitive skin +2.5 record + no irritantsLino-8 (ceramide precursor essential fatty acids)
Powerful corrective anti-aging (retinoid run-ins ≥ 6 months)Maximal - anti-aging 95.2 catalog recordClinical Vitamin A (HPR + Retinol + Retinal - gradual introduction)
Multi-mechanism anti-taskingStrong - tri-action profile (spots 86.7 + redness 91.8)Even In (tranexamic acid + arbutin + kojic + nonapeptide-1)
Vitamin C for sensitive skinStrong - 3 stable derivatives + potentiating ferulic acidC-Tetra E.F. (4.25/5 out of 2 BD reviews)
Retinoid-free anti-aging (pregnancy / breastfeeding)Strong - GHK-Cu Pickart documented + 4 peptidesCopper Peptide (anti-aging 86.7)
Preventive anti-aging 25-35 yearsStrong - 5 layered bioactive peptidesDerma-Peptides (anti-aging 76.5)
Deep hydration for sensitive skinStrong - triple AH + ceramide NG + sphingolipidsHAPCA Filler (sensitive skin +0.5)
First-time retinoid userModerate - prefer A Retinyl Retinoate vs Clinical Vitamin AA Retinyl Retinoate (sensitive skin -1,2)
5-ceramide barrier identified for combination and oily skinFort - signature formulative TheramidCeramide Treatment (normal to oily skin 91)
Budgeting for accessibilityLimited - prefer CeraVe / The Ordinary / SVRPrefer accessible alternatives according to segment
Very dry skin looking for an emollient cream formatLimited - prefer CeraVe / Avène cream formatCeraVe Moisturizing Cream (~€12/340 g)
Severe acne skinLimited - Lino-8 score imperfections -38.2Prefer Nooance Clarifying Care or The Ordinary BHA
Pregnancy / breastfeeding (avoid retinoids)Strong non-retinoid - Copper Peptide + AZID + Lino-8 + HAPCAAvoid Clinical Vitamin A + A Retinyl Retinoate

Everything you need really know.

Are Theramid ceramides superior to CeraVe ceramides?
Ceramide diversity criterion, Theramid identifies by name 5 types (NG, NP, AP, AS, NS, EOP) in its Ceramide Treatment, which is objectively superior to the diversity reported by CeraVe (3 ceramides: 1, 3 and 6-II). However, CeraVe retains three advantages : MVE Technology (documented 24-hour sustained release), a greater volume of published independent clinical studies, and a more emollient cream format at a much lower price (~12 € vs ~50 € for Theramid). The choice between the two depends on the priority criterion Theramid's formulative diversity and premium quality of execution, CeraVe's accessibility and independent clinical data.
Which Theramid serum is right for sensitive skin?
For sensitive or reactive skin, several references in the Theramid catalog are objectively suitable : Lino-8 (+2.5 sensitive, no irritants detected) is the most tolerant formulative reference. AZID (+0.1 sensitive, redness 93.5) is exceptional in cases of rosacea. HAPCA Filler (+0.5 sensitive) for deep hydration. C-Tetra E.F. (0.0 sensitive) for the radiance routine. Strictly avoid on sensitive skin: Clinical Vitamin A (-6.9 sensitive, potent tri-retinoid).
Is Clinical Vitamin A Theramid as powerful as a medical retinoid cream?
No, and this distinction is important. The Clinical Vitamin A is a cosmetic serum combining three cosmetic retinoids (Hydroxypinacolone Retinoate, Retinol, Retinal). Prescription retinoid cream contains tretinoin (pure retinoic acid) or prescription retinoids such as tazarotene. These molecules have a more powerful action but are also more irritating., prescribed under medical supervision. Clinical Vitamin A remains in the clinical-grade cosmetics segment« anti-aging score of 95.2 (the highest in the Theramid catalog), mandatory phasing-in, but without the potency of a medical retinoid. For profiles requiring a medical retinoid protocol, a dermatological consultation remains necessary..
Are there better alternatives to Theramid for ceramides?
«Best» depends on priority criteria. For the formulative and premium diversity criteria, Ceramide Treatment Theramid, with its 5 identified ceramides, is objectively superior to most available references. For the independent published clinical data and affordability criteria, CeraVe Moisturizing Cream remains the benchmark (~€12, MVE Technology, independent studies). For atopic skin criteria, Avene XeraCalm A.D. offers a specifically documented formulation (~€15). For the gel-cream format with niacinamide criterion, Byoma Gel-Cream (~€16) is an intermediate option. Azelaic acid at 15 % well tolerated on rosacea, AZID Theramid remains the formulative reference demonstrated by BeautyDecoded reviews (5/5 out of 5 reviews).
When should you consider a Theramid skin care product rather than an affordable dermo-cosmetic?
For a consumer looking for a active-centric serum with specifically identified active ingredients (multi-type ceramides, stratified peptides, tri-retinoid combination, cosmetic tranexamic acid), Theramid offers a consistent level of premium formulative quality. For a consumer whose budget favors accessibility with documented assets at communicated concentrations, The Ordinary, SVR or La Roche-Posay remain serious alternatives at much lower prices.. For specific problems where Theramid is superior (AZID 15 % on rosacea with exceptional tolerance, AZID confirmed 5/5 out of 5 reviews), price arbitrage may tip in Theramid's favor.
Can Theramid skincare be combined with retinol?
Yes - Theramid ceramides are precisely what we associate with retinol. for limit irritation and support the skin barrier during retinoid action. Niacinamide is even more effective for this purpose (stimulation of endogenous ceramides + anti-inflammatory). The ideal order for an evening routine : retinol (or Clinical Vitamin A Theramid for resistant skin), ceramides on top to seal in moisture and repair the barrier. Ceramide Treatment Theramid is particularly well suited to this strategy.. For retinoid beginners, l'A Retinyl Retinoate Theramid offers a gentler introduction than Clinical Vitamin A.
Can Theramid products be used during pregnancy?
Ceramides, HA, peptides (Copper Peptide, Derma-Peptides), panthenol, ferulic acid, stable vitamin C derivatives are generally compatible.. Absolutely avoid : Clinical Vitamin A (tri-retinoid HPR + Retinol + Retinal - strictly contraindicated in pregnancy and breastfeeding, documented teratogenicity of systemic retinoids as a precautionary principle) and A Retinyl Retinoate (retinaldehyde + retinol ester - same contraindication). Azelaic acid (AZID) and tranexamic acid (Even In) are Classically not recommended as a precaution without documented absolute contraindication. Pregnancy-friendly anti-aging routine : Copper Peptide (anti-aging 86.7 retinoid-free) + (anti-aging 86.7 retinoid-free) + (anti-aging 86.7 retinoid-free) Derma-Peptides (anti-aging 76.5 retinoid-free) + (anti-aging 76.5 retinoid-free) + (anti-aging 76.5 retinoid-free) Lino-8 (sensitive skin +2.5 record, no irritant) + + (no irritant) HAPCA Filler (deep moisturizing, sensitive skin +0.5). Consult your doctor or midwife for any routine changes during pregnancy.
What is the BeautyDecoded application?
BeautyDecoded allows you to choose cosmetics adapted to your skin type thanks to INCI analysis. The application analyzes formulations and generates compatibility scores for 80 skin types. 10 Theramid serums are listed, including 2 references validated by user reviews (AZID 5/5 out of 5 reviews, C-Tetra E.F. 4,25/5 out of 2 reviews). For Theramid specifically, BeautyDecoded's systematic analysis enabled us to’update an earlier conclusion («AZID is the positive exception, the rest lack rigor») into a a much more nuanced reading Theramid is a serious range of documented active serums, with formulative transparency above the average in the clean beauty premium segment. Algorithmic analysis also enabled us to objectively map the compatibility of each serum according to skin profiles andidentify priority references (AZID rosacea, Lino-8 sensitive skin, Clinical Vitamin A powerful corrective anti-aging). It does not constitute a medical consultation.

Plastic and aesthetic surgeon. Founder of BeautyDecoded.

15 yearsclinical expertise
200 000+YouTube subscribers
70 000+Instagram & TikTok followers

«Ceramides are one of the active ingredients I talk about most in consultations. Not because it's trendy - because it's biologically sound. Replenishing intercellular cement with the same molecules naturally present in the skin is the most rational approach to treating a deficient barrier. Among marques ceramides, Theramid stands out for its transparency: 5 ceramides are specifically identified in Ceramide Treatment, and their presence is repeated in other references (AZID, HAPCA Filler). This is a good thing to recognize. BeautyDecoded's analysis confirms this structural diagnosis: AZID is the leading formulating reference, with an exceptional redness score of 93.5, sensitive skin +0.1 (a remarkable result for an active ingredient at 15 %, which is usually irritating), and a score of 5/5 out of 5 reviews. Tolerance for rosacea is confirmed by BD users, who report finally being able to tolerate an AA 15 % after having abandoned it for other marquess. Lino-8 is the catalog's tolerance nugget: sensitive skin +2.5 catalog record, no irritants detected in INCI - for a patient with sensitive skin, rosacea or post-procedure (laser, peel), this is probably the Theramid serum to prescribe first. Clinical Vitamin A is the most powerful cosmetic retinoid formulation in the Theramid catalog, with an anti-aging record of 95.2, and one of the highest BeautyDecoded anti-aging scores of any catalog - on a par with Retinol 0.3 % Typology (anti-aging 93.5), Retinal 0.2 % The Ordinary (anti-aging 93.5), Retinol 0.3 SkinCeuticals (anti-aging 93.5) - but reserved for retinoid-experienced profiles (≥ 6 months without irritation), strictly contraindicated for reactive skin, rosacea, pregnancy or breastfeeding. The price differential with accessible dermo-cosmetic references remains the main arbitration factor - for consumers valuing premium formulative transparency and sophisticated multi-active layering, Theramid offers a consistent level of quality; for consumers seeking the best active-price ratio, more accessible alternatives exist (CeraVe for ceramides, The Ordinary for peptides, Nooance for azelaic acid). Three editorial recommendations: (1) for rosacea and azelaic acid 15 % with documented tolerance: AZID is the catalog reference and one of the best-performing anti-redness serums in the entire BD database; (2) for sensitive, rosacea-prone or post-procedure skin: Lino-8 as first-line treatment (no irritant detected, sensitive skin +2.5 record); (3) for powerful corrective anti-aging in retinoid-savvy profiles: Clinical Vitamin A as a very gradual introduction (1 evening/week × 4 weeks, then 2 evenings, then 3), SPF 50+ morning mandatory, contraindicated in pregnancy and breastfeeding. »

Analyse a Theramid product on your skin profile.

The BeautyDecoded application lets you scan any cosmetic product to visualize its suitability for your skin type and needs, based on INCI analysis - particularly useful for arbitrating between the 10 serums in the Theramid catalog according to your personal profile (Lino-8 sensitive skin / AZID rosacea / Clinical Vitamin A corrective anti-aging / Copper Peptide retinoid-free anti-aging / HAPCA Filler hydration) and for calibrating a protocol for the gradual introduction of a powerful retinoid like Clinical Vitamin A.

Application available on iOS and Android
Dr Sylvain David Plastic and aesthetic surgeon - Founder of BeautyDecoded

Information for educational purposes only, not a substitute for medical consultation. BeautyDecoded is an artificial intelligence cosmetic analysis application and is not a medical diagnostic tool. Theramid is a cosmetics brand developed by NicheBeautyLab - its products are not medical devices. This analysis is based on 10 Theramid sera algorithmically analyzed by BeautyDecoded, including 2 references validated by user reviews (AZID 5/5 out of 5 reviews, C-Tetra E.F. 4.25/5 out of 2 reviews). This analysis updates an earlier conclusion published by BeautyDecoded on Theramid («AZID is the positive exception, the rest lack rigor») on the front page. a more nuanced reading reflecting the enrichment of the BD base from 2 to 10 sera analyzed. Retinoid precautions (Clinical Vitamin A, A Retinyl Retinoate) SPF 50+ morning mandatory for the entire duration of use and 4 weeks after discontinuation, strictly contraindicated during pregnancy and breast-feeding (documented teratogenicity of retinoids as a precautionary principle), do not combine with AHA/BHA on the same evening (so no simultaneous Clinical Vitamin A + Even In - alternate). Possible transient skin purging phenomenon when starting retinoids (transient accentuation of acne for 4-8 weeks) - expected reaction, not a permanent adverse effect. Clinical Vitamin A is strictly contraindicated on reactive, rosaceous or atopic skin. (Sensitive skin score -6.9, redness score -216.8 - the most negative in the Theramid catalog) - reserved for retinoid-experienced profiles (≥ 6 months' use of retinol at medium concentration without irritation). AZID (azelaic acid 15 %) and Even In (tranexamic acid) are traditionally not recommended as a precautionary measure during pregnancy, in the absence of documented absolute contraindication. Theramid pregnancy-compatible anti-aging routine Copper Peptide + Derma-Peptides + Lino-8 + HAPCA Filler (retinoid-free references). 48-hour patch test on forearm recommended before facial use for any new active ingredient on reactive skin, particularly for Even In due to its multi-ingredient complexity (kojic acid, mandelic, lactobionic). Realistic timeframe for anti-spot and anti-aging results 8-12 weeks minimum of regular use - not 2-3 weeks. The price differential between Theramid and accessible dermo-cosmetic references (CeraVe, The Ordinary, SVR, La Roche-Posay) must be weighed against the value attributed to Superior formulative transparency (ceramides 5 identified types, peptides 5 stratified, retinoids 3 levels), cumulative formulative diversity, premium workmanship. In the event of a skin reaction to a cosmetic, discontinue use immediately and consult a health professional. This article does not constitute a commercial partnership with the Theramid brand or NicheBeautyLab.