Guide skincare - Ingredients

Azelaic acid - the underestimated multifunctional asset according to a doctor and analyses by BeautyDecoders.

Azelaic acid is a multifunctional active ingredient that acts on acne, pigmentation spots, redness, blackheads and texture. Antibacterial, anti-inflammatory, keratinocyte and melanin regulator, it offers benefits similar to those of exfoliating acids, but is much less irritating. Well tolerated, even by sensitive skin, it can be used at 10-15 % and combines very well with retinol and exfoliating acids.

FamilyDicarboxylic acid (cereals)
MethodVerdict Sensitivity - Dr David's rule
Selection3 products rated by BeautyDecoders

The 5 actions of azelaic acid

Azelaic acid is an underrated and underused cosmetic ingredient. Yet it solves many skin problems: acne, redness, spots, blackheads, texture. Its mechanisms are not all fully understood, but we do know that it «brings order» to cells that have become uncontrollable, whether they produce too much pigment (melasma) or over-react to inflammation (acne, rosacea). Five actions are agreed upon:

01

Antibacterial

It acts on Cutibacterium acnes and Staphylococcus aureus, making it effective against acne.

02

Regulation of keratinocytes

It normalizes their proliferation on the surface: the benefits of exfoliating acids, but less irritating. Different mechanisms, so it combines very well with acids for texture and pores.

03

Lipid reduction

It helps lysis of surface lipids and blackheads, appreciated by combination to oily skin.

04

Anti-stain action

It acts on tyrosinase (melanin enzyme), reduces sun spots and evens skin tone.

05

Anti-inflammatory & antioxidant

Invaluable for skin prone to redness and sensitive skin.

A discovery incidental

Azelaic acid is a dicarboxylic acid derived from the fermentation of cereals (wheat, barley, rye), and also produced on the skin surface by yeast. In fact, this is what led to its discovery.

White spots that put us on the trail

In the late 70s, doctors noticed that a yeast, Malassezia furfur, was creating white spots by destroying pigments in the areas where it was spreading. They realized that it produced azelaic acid, studied it and discovered its impressive depigmenting properties. Since then, interest in this active ingredient has grown steadily.

Concentration and formulation

Products with 10 % azelaic acid are readily available, but the formulation is complex: it comes in powder form, which is difficult to formulate at high concentration. This has two consequences. Firstly, products tend to lint (part of the powder remains on the surface after absorption); the intensity depends on the formulation. Secondly, like all powder ingredients, it matifies the skin after application.

As is often the case, the higher the concentration, the more frequent the side-effects: mainly burning, tingling and itching. On healthy skin, the risk is low; in the case of sensitive skin, it's best to introduce azelaic acid gradually.

Antioxidant, anti-inflammatory, anti-spot, anti-redness, unifying, pore-enhancing: why is such an active ingredient still so rare in cosmetics? No clear answer. Perhaps because it's difficult to formulate, or because marketing relies on «best-selling» actives like hyaluronic acid, or simply because its multiple benefits remain unknown - a question that deserves to be put to the marquess that don't offer it.

Which products to azelaic acid ?

Here are three representative azelaic acid products, with BeautyDecoded scores and user feedback. For a full comparison, see the selection of best azelaic acid serums.

The ratings and review excerpts come from users of the BeautyDecoded application. These reviews are not verified. The Sensitivity Verdict applies the Dr David Rule: a sensitive skin score greater than or equal to 0 indicates a product suitable for sensitive skin, negative an increasing caution.
Azelaic acid 15% + niacinamide - Isispharma

Isispharma Metroruboril A.Z (azelaic acid 15%)

★★★★½4,61/5(18 reviews - solid base)
Pensé rosacée - best redness score

Parapharmacy cream with 15 % azelaic acid, enriched with niacinamide, liquorice and soothing ingredients, specially designed for rosacea and skin prone to redness (excellent redness score at 93,5). Thick texture. Sensitive skin score -1.0 - slight caution. Clearly reduces rosacea and diminishes blemishes according to numerous feedbacks; a little greasy and can fluff up, not necessarily to be used every day.

Scores BeautyDecoded
Dry skin
49
Oily skin
84
Normal to oily
77
Sensitive skin
-1
Imperfections
85
Stains
85
Redness
93,5
⚠ Sensitivity verdict Slight caution (score: -1.0). Not necessarily every day on reactive skin.
User feedback (18 reviews - representative extracts)
★★★★★«Thanks to this cream my rosacea has diminished considerably.»
★★★★★«With 15 % of azelaic acid, helps reduce my spots, a little greasy but effective.»
★★★★«Good anti-redness cream, I use it a few times a week.»
★★★«It fluffs up and leaves my skin dry, little benefit on my rosacea after two tubes.»
Verdict - Azelaic acid 15 % + niacinamide thought for rosacea (redness 93.5, blotchiness 85). Slight caution (-1.0), thick, slightly oily texture that can fluff up. 4.61/5 out of 18 reviews.
Azelaic Acid 10% - Aroma-Zone

Aroma-Zone Azelaic Acid Serum 10%

★★★★4,32/5(19 reviews - solid base)
Blemish-oriented - low price

Serum with 10 % azelaic acid, easy-to-integrate format at a low price, for blemishes and blackheads (blemish score) 90,1). Suitable for combination to oily skin. Sensitive skin score -0.5 - slight caution, but well tolerated. Fast results on blackheads, blackheads and radiance, according to many loyal customers.

Scores BeautyDecoded
Dry skin
42
Oily skin
84
Normal to oily
91
Sensitive skin
-0,5
Imperfections
90,1
Stains
68
Redness
68
⚠ Sensitivity verdict Slight caution (score: -0.5). Well tolerated in practice.
User feedback (19 reviews - representative extracts)
★★★★★«It limits the appearance of blackheads, I highly recommend it for this problem.»
★★★★★«Hormonal acne and blackheads: marked improvement since I started using it.»
★★★★«Results from the first week on skin quality, fewer imperfections, brighter complexion.»
★★★★«Works well on me, simple to integrate into routine.»
Verdict - Low-cost azelaic acid 10 % for blemishes (90.1), easy to integrate on combination to oily skin. Slightly cautious (-0.5) but well tolerated, rapid results on blackheads and blackheads. 4.32/5 out of 19 reviews.
Azelaic acid 10% - The Ordinary

The Ordinary Azelaic Acid Suspension 10%

★★★3,30/5(10 reviews - solid base)
Low price & sensitive skin - but plush

The accessible, minimalist formula with 10 % azelaic acid, with little irritation, is suitable even for sensitive skin (score sensitive skin). 0 - suitable). Good redness score (93,5). Reduces pimples and redness, according to feedback; its major flaw, mentioned by almost all reviews, is the marked fluffing, accentuated when combined with other products, to be applied alone and in a thin layer.

Scores BeautyDecoded
Dry skin
63
Oily skin
42
Normal to oily
56
Sensitive skin
0
Imperfections
51
Stains
78,2
Redness
93,5
✓ Verdict sensitivity Suitable for sensitive skin (score: 0). Not very irritating; apply alone, in a thin layer.
User feedback (10 opinions - representative extracts)
★★★★★«Great product, it reduces my pimples and redness.»
★★★★«I've been using it for a month on my acne spots, I'm very happy with it.»
★★★★«Good price, good composition, suitable for oily skin, but it does fluff up.»
★★«Not convinced: it's extremely fluffy, impossible to put it with anything else.»
Verdict - Minimalist, low-irritation azelaic acid 10 %, suitable for sensitive skin (0), good for redness (93.5) and blemishes (78.2). Near-unanimous major flaw: very fluffy, to be applied alone in a thin layer. 3.30/5 out of 10 reviews.

How to use it in its routine

Azelaic acid is easy to integrate, as it is not very irritating. If initially tingling, start every other day; if well tolerated, use daily. Apply after cleansing and lotion, before sunscreen or moisturizer.

The best combinations: with exfoliating acids, both reduce dead cells by different mechanisms (acids break the bonds between cells, azelaic acid regulates their cycle) - ideal for pores and texture. Use with retinol, The complementary effect on hyperkeratosis and the anti-inflammatory effect help to better withstand irritation. It also combines perfectly with niacinamide.

Why does it reduce pimples? When keratinocyte proliferation gets out of control, it creates hyperkeratinization: dull complexion, accumulation of dead cells, altered pores and blackheads. Rather than a brutal exfoliation (glycolic or lactic acid), azelaic acid forces cells to regulate their development and diminishes hyperkeratinization. Dead cells accumulate less in pores, improving their appearance and reducing the appearance of pimples.

Find the right azelaic acid for your skin profile.

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Your questions about azelaic acid

Is azelaic acid effective against acne?
Yes: it is antibacterial (against acne bacteria), anti-inflammatory, regulates keratinocytes and reduces the hyperkeratinization responsible for blackheads. It's an excellent anti-acne active ingredient, better tolerated than many others, even by sensitive skin.
Does azelaic acid lint the skin?
Some products do, because azelaic acid is a powder, some of which remains on the surface after absorption. The intensity depends on the formulation. Applying a thin layer and allowing it to absorb well before the next treatment limits the phenomenon.
Suitable for sensitive skin and rosacea?
Yes, that's one of its great assets: anti-inflammatory and antioxidant, it's appreciated by skin prone to redness and rosacea. However, it should be introduced gradually for very sensitive skin, as slight tingling may occur at first.
Can azelaic acid and retinol be combined?
Yes, it's even an excellent combination: the two act on hyperkeratosis in a complementary way, and azelaic acid, which is anti-inflammatory, helps to better tolerate the irritation of retinol.
At what concentration should it be used?
Cosmetic products generally range between 10 and 15 %. Higher concentrations are more effective, but also more likely to cause tingling. We often start at 10 %, then adjust according to tolerance.
Dr Sylvain DavidPlastic and aesthetic surgeon - Founder of BeautyDecoded

Information for educational purposes only. It does not replace a medical consultation and must be adapted to each individual. The compatibility scores generated by the application do not prejudge the individual tolerance of each skin type. Azelaic acid is generally well tolerated, but can cause tingling, burning or itching, especially at high concentrations or on sensitive skin: a gradual introduction is recommended. In cases of rosacea or persistent acne, dermatological advice is recommended. A tolerance test should be carried out before using the product for the first time.